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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: ZCCHC13-mediated induction of human liver cancer is associated with the modulation of DNA methylation and the AKT/ERK signaling pathway

Fig. 3

Analysis of the ZCCHC13 subcellular localization and ZCCHC13-specific antibodies in human sera. a The endogenous ZCCHC13 protein was distributed in the nucleus of Huh7 cells. Merged images showed the co-localization between the ZCCHC13 protein and nuclei stained with DAPI. b The recombinant ZCCHC13 protein was expressed at the predicted molecular size of approximately 18 kD, as particularly evident in the lane for the 150 mM imidazole elution buffer. c Responses of serum from patients with HCC and healthy donors to ZCCHC13, as determined using an ELISA (****p < 0.0001)

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