Spray drying OZ439 nanoparticles to form stable, water-dispersible powders for oral malaria therapy

Table 1 Water uptake by spray dried NP powder over 6-month stability time course

Time in oven	0 days	2 months	6 months
Water content (w/w)	Below detection limit (< ~ 4%)	Below detection limit (< ~ 4%)	6.26%

Immediately following spray drying and after 2 months in the oven, water content was below the detection limit of the KF titrator. By the end of 6 months, the powder had accumulated a small amount of water, which did not adversely affect OZ439 solubilization

ISSN: 1479-5876