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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Spray drying OZ439 nanoparticles to form stable, water-dispersible powders for oral malaria therapy

Fig. 5

Effect of the amount of HPMC E3 added prior to spray drying on the redispersion of nanoparticles from the spray dried powder. Size distributions of nanoparticles immediately after formation (blue square), 3 h after formation (yellow circle), upon redispersion after spray drying with 0.5 (red triangle) and 1 (green triangle) mass equivalents of added HPMC E3. NPs sprayed 1:1 with HPMC E3 (green) redispersed better then NPs sprayed 1:0.5 with E3 (red), based on the size of the ~ 5000 nm aggregation peak seen by DLS. Both spray dried formulations redispersed to a size smaller than the size to which the original NPs had ripened by 3 h after formation

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