Fig. 2
From: Longitudinal heterogeneity in glioblastoma: moving targets in recurrent versus primary tumors
Target investigation by Multiplex ligation-dependent probe amplification (MLPA). a Overview of cases and the respective copy number aberrations status of the selected targets. b Graphs illustrate correlation of target status in the investigated cohort of paired tissue samples. The thickness of lines visualizes the number of affected patients. A status change between primary and recurrent tumor tissue is indicated by encircled numbers, reflecting the percentage of affected patients (numbers rounded). The boxes indicate the portion of copy number aberrations: No CNA, low gain, high gain, and focal amplification