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Table 4 Univariate log-rank analysis conducted on D2

From: Nuclear shape, architecture and orientation features from H&E images are able to predict recurrence in node-negative gastric adenocarcinoma

Variable

HR (95% CI)

P value

Age (< 60 vs. ≥ 60)

0.66 (0.13–3.35)

0.621

T-stage (T1/T2 vs. T3/T4)

2.18 (1.10–4.31)

0.024

Histology (W/M vs. poorly)

3.66 (1.12–11.98)

0.032

Chemotherapy (yes vs. no)

3.89 (0.92–16.47)

0.065

Invasion depth (out vs. in)

1.87 (1.03–3.39)

0.039

Tumor diameter (< 5 cm vs. ≥ 5 cm)

2.15 (0.88–5.22)

0.091

Manual nuclear atypia grading (low vs. high)

3.08 (0.90–10.49)

0.072

NGAHIC (positive vs. negative)

4.14 (1.28–13.29)

0.017

  1. CI confidence interval, HR hazard ratio; W/M: well and moderate-differentiated, poorly: poorly differentiated, out: out of serosa, in: invasion of serosa
  2. P value in italic is statistically significant, P < 0.05