Table 1 Summary of histomorphometric features extracted from TMA

Nuclear shape

Area ratio, distance ratio, SD of distance, distance ratio, perimeter ratio, variance of distance, fractal dimension, smoothness, invariant moment 1–7, Fourier descriptor 1–10: min/max, mean, SD, median

Nuclear texture

Contrast, energy, entropy, inverse variance, invariant moment: mean, SD from each channel

Nuclear orientation map

Contrast energy, contrast inverse moment, contrast average, contrast variance, contrast entropy, intensity average, intensity variance, intensity entropy, entropy, energy, correlation, information measure 1, information measure 2: mean, SD, range

VD

Perimeter, chord, area: SD, min/max, disorder, average

DT

Side length, triangle area: min/max, mean, standard deviation, median, disorder

In total