TY - JOUR AU - Li, Zibo AU - Lin, Yukun AU - Zhang, Shuhui AU - Zhou, Lin AU - Yan, Guixi AU - Wang, Yuehua AU - Zhang, Mengdi AU - Wang, Mengqi AU - Lin, Haihong AU - Tong, Qiaozhen AU - Duan, Yongjian AU - Du, Gangjun PY - 2019 DA - 2019/03/18 TI - Emodin regulates neutrophil phenotypes to prevent hypercoagulation and lung carcinogenesis JO - Journal of Translational Medicine SP - 90 VL - 17 IS - 1 AB - Hypercoagulation and neutrophilia are described in several cancers, however, whether they are involved in lung carcinogenesis is currently unknown. Emodin is the main bioactive component from Rheum palmatum and has many medicinal values, such as anti-inflammation and anticancer. This study is to investigate the contributions of neutrophils to the effects of emodin on hypercoagulation and carcinogenesis. SN - 1479-5876 UR - https://doi.org/10.1186/s12967-019-1838-y DO - 10.1186/s12967-019-1838-y ID - Li2019 ER -