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Table 2 Subjective, heart rate and ventilatory parameters obtained during consecutive days of maximal exercise testing

From: Diagnostic sensitivity of 2-day cardiopulmonary exercise testing in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Variable Controls Day 1 ME/CFS Day 1 Controls Day 2 ME/CFS Day 2 ‘Group’ effect p-value ‘Time’ effect p-value ‘Group’ × ‘Time’ interaction p-value
Chalder Fatigue Score 11.2 (0.6) 20.3 (6.8) 11.2 (0.6) 25.3 (7.0) <0.001 0.005 0.005
Resting
 HR (bpm) 69.5 (8.4) 74.0 (12.1) 70.1 (10.9) 72.0 (12.0) 0.47 0.60 0.35
 VO2 (ml/kg/min) 4.1 (0.8) 4.5 (1.4) 4.1 (0.7) 4.1 (1.3) 0.57 0.46 0.49
Steady state (30 W for female, 40 W for male)
 HR (bpm) 100.6 (11.1) 106.5 (12.6) 101.0 (12.7) 104.5 (14.2) 0.31 0.71 0.57
 VO2 (ml/kg/min) 11.6 (1.3) 11.4 (1.3) 11.4 (1.3) 11.3 (2.1) 0.80 0.49 0.83
 RPE 8.3 (1.6) 10.5 (1.9) 7.5 (1.7) 10.4 (2.3) 0.001 0.32 0.40
Ventilatory threshold
 HR (bpm) 122.4 (13.2) 124.0 (18.3) 120.8 (14.2) 117.4 (17.6) 0.89 0.03 0.17
 WR (watts) 90.5 (17.1) 87.8 (29.6) 88.0 (16.7) 72.5 (27.7) 0.37 <0.001 0.003
 VO2 (ml/kg/min) 16.5 (2.0) 15.9 (4.1) 15.9 (1.5) 15.4 (3.4) 0.69 0.08 0.82
 RPE 10.8 (1.9) 13.0 (1.4) 10.7 (1.6) 12.6 (2.0) 0.003 0.41 0.63
Maximal exercise
 HR (bpm) 170.3 (10.0) 167.8 (20.0) 170.9 (11.0) 167.0 (15.7) 0.60 0.93 0.66
 WR (watts) 172.0 (35.5) 154.4 (56.0) 174.0 (36.6) 152.5 (51.7) 0.32 0.97 0.27
 VO2 (ml/kg/min) 29.9 (6.1) 27.3 (9.2) 30.3 (6.2) 27.4 (8.8) 0.40 0.54 0.73
 RPE 16.4 (1.4) 17.5 (1.4) 17.0 (1.6) 17.6 (1.3) 0.11 0.20 0.40
  1. Values are mean (SD), Italic text indicates p-value < 0.05
  2. ME/CFS Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, HR heart rate, VO2 volume of oxygen uptake, ml millilitres, kg kilogram, min minute, RPE rating of perceived exertion, WR work rate