|
Variable
|
Controls Day 1
|
ME/CFS Day 1
|
Controls Day 2
|
ME/CFS Day 2
|
‘Group’ effect p-value
|
‘Time’ effect p-value
|
‘Group’ × ‘Time’ interaction p-value
|
|---|
|
Chalder Fatigue Score
|
11.2 (0.6)
|
20.3 (6.8)
|
11.2 (0.6)
|
25.3 (7.0)
|
< 0.001
|
0.005
|
0.005
|
|
Resting
|
|
HR (bpm)
|
69.5 (8.4)
|
74.0 (12.1)
|
70.1 (10.9)
|
72.0 (12.0)
|
0.47
|
0.60
|
0.35
|
|
VO2 (ml/kg/min)
|
4.1 (0.8)
|
4.5 (1.4)
|
4.1 (0.7)
|
4.1 (1.3)
|
0.57
|
0.46
|
0.49
|
|
Steady state (30 W for female, 40 W for male)
|
|
HR (bpm)
|
100.6 (11.1)
|
106.5 (12.6)
|
101.0 (12.7)
|
104.5 (14.2)
|
0.31
|
0.71
|
0.57
|
|
VO2 (ml/kg/min)
|
11.6 (1.3)
|
11.4 (1.3)
|
11.4 (1.3)
|
11.3 (2.1)
|
0.80
|
0.49
|
0.83
|
|
RPE
|
8.3 (1.6)
|
10.5 (1.9)
|
7.5 (1.7)
|
10.4 (2.3)
|
0.001
|
0.32
|
0.40
|
|
Ventilatory threshold
|
|
HR (bpm)
|
122.4 (13.2)
|
124.0 (18.3)
|
120.8 (14.2)
|
117.4 (17.6)
|
0.89
|
0.03
|
0.17
|
|
WR (watts)
|
90.5 (17.1)
|
87.8 (29.6)
|
88.0 (16.7)
|
72.5 (27.7)
|
0.37
|
< 0.001
|
0.003
|
|
VO2 (ml/kg/min)
|
16.5 (2.0)
|
15.9 (4.1)
|
15.9 (1.5)
|
15.4 (3.4)
|
0.69
|
0.08
|
0.82
|
|
RPE
|
10.8 (1.9)
|
13.0 (1.4)
|
10.7 (1.6)
|
12.6 (2.0)
|
0.003
|
0.41
|
0.63
|
|
Maximal exercise
|
|
HR (bpm)
|
170.3 (10.0)
|
167.8 (20.0)
|
170.9 (11.0)
|
167.0 (15.7)
|
0.60
|
0.93
|
0.66
|
|
WR (watts)
|
172.0 (35.5)
|
154.4 (56.0)
|
174.0 (36.6)
|
152.5 (51.7)
|
0.32
|
0.97
|
0.27
|
|
VO2 (ml/kg/min)
|
29.9 (6.1)
|
27.3 (9.2)
|
30.3 (6.2)
|
27.4 (8.8)
|
0.40
|
0.54
|
0.73
|
|
RPE
|
16.4 (1.4)
|
17.5 (1.4)
|
17.0 (1.6)
|
17.6 (1.3)
|
0.11
|
0.20
|
0.40
|
- Values are mean (SD), Italic text indicates p-value < 0.05
- ME/CFS Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, HR heart rate, VO2 volume of oxygen uptake, ml millilitres, kg kilogram, min minute, RPE rating of perceived exertion, WR work rate
