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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Chronic abdominal vagus stimulation increased brain metabolic connectivity, reduced striatal dopamine transporter and increased mid-brain serotonin transporter in obese miniature pigs

Fig. 4

Left panels—examples of reconstructed normalized volumes obtained after the administration of 123I ioflupane in sham versus stimulated animals. The colors represented pixel-wise modeled SPECT dynamic image series according to Ichise i.e., the binding potential overlaid on the MRI template of the pig brain atlas. Red VOIs corresponded to DAT-rich areas whereas yellow VOIs represented SERT-rich areas. Right panel—binding potential for DAT and SERT in sham versus stimulated groups obtained from region-based analysis. *Indicates a significant difference at P < 0.001

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