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Table 2 Descriptive data

From: Osteoclastic expression of higher-level regulators NFATc1 and BCL6 in medication-related osteonecrosis of the jaw secondary to bisphosphonate therapy: a comparison with osteoradionecrosis and osteomyelitis

  Group Min Max Mean Median IQR SD
Anti-NFATc1 staining
 Nuclear expression
  NFATc1 + osteoclasts per ROI (osteoclasts/mm2) MRONJ (BP) 0.0 171.7 31.2 25.1 45.9 36.1
OM 0.0 31.4 7.0 0.0 14.1 9.8
ORN 0.0 36.5 11.4 1.8 22.3 13.8
CONTROL 0.0 5.8 0.8 0.0 0.6 1.9
  Labeling index (%/100) MRONJ (BP) 0 1 0.569 0.573 0.790 0.381
OM 0 1 0.304 0 0.650 0.396
ORN 0 1 0.424 0.248 1 0.440
CONTROL 0 0.420 0.065 0 0.060 0.144
Anti-BCL6 staining
 Cytoplasmic expression
  BCL6 + osteoclasts per ROI (osteoclasts/mm2) MRONJ (BP) 0.0 113.1 33.2 29.1 29.4 25.9
OM 0.0 43.4 11.4 9.2 16.5 12.4
ORN 0.0 141.3 19.7 5.6 13.6 35.8
CONTROL 0.0 9.2 1.7 0.0 3.5 3.1
  Labeling index (%/100) MRONJ (BP) 0 1 0.760 0.860 0.380 0.300
OM 0 1 0.445 0.444 0.860 0.391
ORN 0 1 0.714 0.839 0.560 0.349
CONTROL 0 0.370 0.100 0 0.300 0.163
Nuclear expression
 BCL6 + osteoclasts per ROI (osteoclasts/mm2) MRONJ (BP) 0 73.4 17.6 13.1 21.4 16.9
OM 0 11.4 2.9 2.1 4.1 3.7
ORN 0 92.5 10.8 2.5 10.4 23.4
CONTROL 0 9.3 1.9 0 4.0 3.3
 Labeling index (%/100) MRONJ (BP) 0 1 0.469 0.483 0.58 0.329
OM 0 0.72 0.160 0.075 0.29 0.218
ORN 0 1 0.416 0.282 0.46 0.342
CONTROL 0 0.56 0.109 0 0.27 0.189
Nuclear BCL6 + osteoclasts to cytoplasmic BCL6 + osteoclasts (%/100) MRONJ (BP) 0 1 0.513 0.503 0.433 0.308
OM 0 0.450 0.164 0.127 0.355 0.177
ORN 0 0.778 0.460 0.500 0.333 0.237
CONTROL 0 1 0.243 0 0.550 0.424
  1. Min minimum, Max maximum, IQR interquartile range, SD standard deviation, ROI region of interest, MRONJ (BP) medication-related osteonecrosis of the jaw secondary to bisphosphonate therapy, OM osteomyelitis, ORN osteoradionecrosis, NFATc1 nuclear factor of activated T-cells, cytoplasmic 1, BCL6 B-cell lymphoma 6