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Table 2 Basic characteristics of participants in stage-1 study
| HC | NA | MA | OA | ESKD | UTI | BC | |
|---|---|---|---|---|---|---|---|
| Number | 14 | 16 | 11 | 12 | 13 | 8 | 8 |
| Age | 47.0 ± 8.6 | 49.9 ± 10.2 | 64.3 ± 6.7* | 60.4 ± 8.9* | 64.3 ± 12.2* | 49.4 ± 13.3 | 62.3 ± 10.1* |
| Gender (male/female) | 9/5 | 7/9 | 4/7 | 10/2 | 11/2 | 5/3 | 2/6 |
| eGFR (ml/min/1.73 m2) | 101.4 [95.9–110.3] | 107.6 [90.6–136.3] | 71.1 [40.3–112.1]* | 50.5 [30.7–80.7]* | 11.9 [8.6–14.7]* | 100.4 [84.2–111.9] | 113.8 [93.9–140.9] |
| ACR (mg/g) | 5.2 [2.9–8.5] | 6.4 [4.8–12.6] | 120.6 [85.8–216.6]* | 685.9 [414.4–3094.0]* | 643.5 [546.3–890.3]* | 8.0 [4.4–12.7] | 10.7 [7.3–15.0] |
| Glu (mmol/L) | 5.7 [5.2–5.9] | 12.0 [8.4–16.8]* | 8.9 [6.8–16.4]* | 9.6 [6.4–12.8]* | 5.7 [4.8–9.2] | 5.8 [4.9–6.0] | 5.7 [5.5–5.9] |
| HbA1c (%) | 4.9 [4.6–5.3] | 10.1 [7.8–10.6]* | 8.3 [6.8–11.2]* | 8.6 [6.2–9.0]* | 6.1 [5.3–8.0] | 5.3 [4.9–5.5] | 4.9 [4.6–5.5] |
| SBP (mmHg) | 119.2 ± 7.5 | 126.3 ± 9.5 | 137.5 ± 13.1* | 147.6 ± 21.9* | 155.5 ± 24.6* | 121.9 ± 11.5 | 127.1 ± 12.4 |
| DBP (mmHg) | 76.4 ± 6.6 | 79.3 ± 8.2 | 81.6 ± 9.1 | 81.7 ± 9.8 | 78.3 ± 12.6 | 74.9 ± 5.5 | 76.4 ± 6.5 |
| Urinary NAG/Cr (U/mol) | 0.43 [0.38–0.72] | 0.60 [0.44–1.14] | 1.30 [0.45–3.70]* | 1.90 [0.84–4.81]* | 1.71 [1.14–2.60]* | 0.51 [0.37–0.74] | 1.33 [0.54–2.34]* |
