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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Computer-aided assessment of the extra-cellular matrix during pancreatic carcinogenesis: a pilot study

Fig. 3

Computer-aided simulation of pancreatic ECM degradation (ac). A statistically significant difference was found when compared the number of cycles necessary to erode the ECM in normal parenchyma versus parenchyma affected by pancreatitis and PDAC. A statistically significant difference was also found comparing the number of cycles (d) necessary to erode the ECM infiltrating the parenchyma affected by pancreatitis and that of PDAC. Also, when we analyzed the velocity of degradation (e) we found that this simulated phenomenon is faster in pancreatitis and PDAC than in natural pancreatic tissue. In contrast, no significant statistically differences were found when compared the simulated velocity of degradation between pancreatitis and PDAC (e). ***p < 0.001 by Student’s t-test; **p < 0.01 by Student’s t-test

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