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Table 3 Correlations between clinical data, tissue remodeling responses, and dermal sodium

From: Dermal tissue remodeling and non-osmotic sodium storage in kidney patients

Variables R p-value
A. Dietary sodium intake and lymphangiogenesis
 Plasma sodium vs. podoplanin expression 0.656 0.028
 Urine sodium vs. podoplanin expression 0.709 0.022
B. Dietary sodium intake and dermal sodium
 Plasma sodium vs. dermal sodium concentration − 0.619 0.042
C. Obesity, age and proteoglycans
 Age vs. mRNA expression of HAS3 0.530 0.042
 Body weight vs. hyaluronan expression 0.503 0.047
 BMI vs. versican expression 0.562 0.024
 BMI vs. mRNA expression of CHST11 0.589 0.021
D. Proteoglycans and lymphangiogenesis
 mRNA expression of CHSY1 vs. mRNA expression of VEGF-C 0.571 0.026
 mRNA expression of CHSY1 vs. mRNA expression of podoplanin 0.546 0.035
 mRNA expression of UST vs. mRNA expression of VEGF-C 0.679 0.005
 mRNA expression of UST vs. mRNA expression of Podoplanin 0.625 0.001
 mRNA expression of HAS2 vs. mRNA expression of VEGF-C 0.757 0.001
 mRNA expression of VCAN vs. mRNA expression of podoplanin 0.600 0.018
 mRNA expression of NDST1 vs. mRNA expression of podoplanin 0.704 0.003
 mRNA expression of CHST11 vs. mRNA expression of podoplanin 0.671 0.006
E. Proteoglycans and fibrosis
 mRNA expression of VCAN vs. mRNA expression of collagen I 0.557 0.031
 mRNA expression of NDST1 vs. mRNA expression of collagen I 0.629 0.012
 mRNA expression of CHST11 vs. mRNA expression of collagen I 0.546 0.035
 mRNA expression of UST vs. mRNA expression of collagen I 0.589 0.021
 mRNA expression of HS6ST1 vs. mRNA expression of collagen I 0.514 0.050
F. Proteoglycans and inflammation
 mRNA expression of HSPE vs. CD68 expression 0.539 0.038
 mRNA expression of HAS2 vs. MCP1 expression − 0.554 0.032
 mRNA expression of UST vs. MCP1 expression − 0.621 0.013
 Heparan sulfate expression (JM403) vs. CD3 expression 0.518 0.048
G. Renal failure and inflammation
 Proteinuria vs. CD68 expression 0.730 0.007
 Proteinuria vs. MCP-1 expression 0.614 0.034
 Systolic blood pressure vs. CD68 expression 0.649 0.007
 eGFR vs. CD68 expression 0.577 0.019
H. Dermal sodium and inflammation
 Dermal sodium storage vs. mRNA expression of CCL2 − 0.582 0.023
  1. Correlations are performed on the Z-scores of the values of donors and preemptive patients