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Table 1 Top 10 GO enrichment analyses of up-regulated and down-regulated DEGs

From: Comprehensive bioinformatics analysis of acquired progesterone resistance in endometrial cancer cell line

Category Term Count p-value
Up-regulated
 BP GO:0009952 ~ anterior/posterior pattern specification 14 1.65E−08
 CC GO:0005615 ~ extracellular space 56 3.21E−07
 MF GO:0043565 ~ sequence-specific DNA binding 30 2.32E−06
 BP GO:0032526 ~ response to retinoic acid 8 2.57E−05
 CC GO:0005576 ~ extracellular region 57 3.21E−05
 CC GO:0005578 ~ proteinaceous extracellular matrix 17 1.07E−04
 BP GO:0048704 ~ embryonic skeletal system morphogenesis 7 1.80E−04
 CC GO:0009986 ~ cell surface 25 2.58E−04
 BP GO:0030198 ~ extracellular matrix organization 14 3.68E−04
 BP GO:0002474 ~ antigen processing and presentation of peptide antigen via MHC class I 6 4.30E−04
Down-regulated
 BP GO:0042472 ~ inner ear morphogenesis 6 0.001957
 BP GO:0060021 ~ palate development 7 0.001967
 BP GO:0070830 ~ bicellular tight junction assembly 5 0.002114
 BP GO:0030198 ~ extracellular matrix organization 11 0.002153
 CC GO:0016328 ~ lateral plasma membrane 6 0.002206
 CC GO:0032587 ~ ruffle membrane 7 0.003009
 CC GO:0005923 ~ bicellular tight junction 8 0.003557
 BP GO:0001525 ~ angiogenesis 11 0.005387
 BP GO:0007165 ~ signal transduction 33 0.005738
 BP GO:0007156 ~ homophilic cell adhesion via plasma membrane adhesion molecules 9 0.0061
  1. Count: number of DEGs that hit in the term