Table 1 Top 10 GO enrichment analyses of up-regulated and down-regulated DEGs
Category | Term | Count | p-value |
|---|---|---|---|
Up-regulated | |||
 BP | GO:0009952 ~ anterior/posterior pattern specification | 14 | 1.65E−08 |
 CC | GO:0005615 ~ extracellular space | 56 | 3.21E−07 |
 MF | GO:0043565 ~ sequence-specific DNA binding | 30 | 2.32E−06 |
 BP | GO:0032526 ~ response to retinoic acid | 8 | 2.57E−05 |
 CC | GO:0005576 ~ extracellular region | 57 | 3.21E−05 |
 CC | GO:0005578 ~ proteinaceous extracellular matrix | 17 | 1.07E−04 |
 BP | GO:0048704 ~ embryonic skeletal system morphogenesis | 7 | 1.80E−04 |
 CC | GO:0009986 ~ cell surface | 25 | 2.58E−04 |
 BP | GO:0030198 ~ extracellular matrix organization | 14 | 3.68E−04 |
 BP | GO:0002474 ~ antigen processing and presentation of peptide antigen via MHC class I | 6 | 4.30E−04 |
Down-regulated | |||
 BP | GO:0042472 ~ inner ear morphogenesis | 6 | 0.001957 |
 BP | GO:0060021 ~ palate development | 7 | 0.001967 |
 BP | GO:0070830 ~ bicellular tight junction assembly | 5 | 0.002114 |
 BP | GO:0030198 ~ extracellular matrix organization | 11 | 0.002153 |
 CC | GO:0016328 ~ lateral plasma membrane | 6 | 0.002206 |
 CC | GO:0032587 ~ ruffle membrane | 7 | 0.003009 |
 CC | GO:0005923 ~ bicellular tight junction | 8 | 0.003557 |
 BP | GO:0001525 ~ angiogenesis | 11 | 0.005387 |
 BP | GO:0007165 ~ signal transduction | 33 | 0.005738 |
 BP | GO:0007156 ~ homophilic cell adhesion via plasma membrane adhesion molecules | 9 | 0.0061 |