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Table 3 Association of NLR with ESRD events among total CKD patients and stratified by stage of CKD

From: Neutrophil-to-lymphocyte ratio and incident end-stage renal disease in Chinese patients with chronic kidney disease: results from the Chinese Cohort Study of Chronic Kidney Disease (C-STRIDE)

NLR ratio Model 1 Model 2
HR (95% CI) HR (95% CI) 
Total CKD patients (n = 938)
 <  2.09 1.00 (Ref)  1.00 (Ref) 
 ≥ 2.09 2.59 (1.72, 3.90) 1.16 (0.74, 1.81)
 p for trend < 0.001 0.512
eGFR ≥ 60 mL/min (n = 360)
 < 2.09 1.00 (Ref)  1.00 (Ref) 
 ≥ 2.09 1.77 (0.36, 8.87) 1.57 (0.21, 11.98)
 p for trend 0.485 0.663
30 ≤ eGFR < 60 mL/min (n = 345)
 < 2.09 1.00 (Ref)  1.00 (Ref) 
 ≥ 2.09 0.98 (0.50, 1.92) 0.507 (0.23, 1.11)
 p for trend 0.95 0.089
15 ≤ eGFR < 30 mL/min (n = 233)
 < 2.09 1.00 (Ref)  1.00 (Ref) 
 ≥ 2.09 2.11 (1.18, 3.76) 2.124 (1.10, 4.10)
 p for trend 0.012 0.025
  1. Model 1: Adjusted for age, gender
  2. Model 2: Model 1 + smoking, drinking, diabetes, hypertension, cardiovascular diseases, hyperuricemia, urine albumin/creatinine ratio, chronic kidney disease-mineral and bone disorder, hemoglobin, hyperlipidaemia, eGFR