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Table 3 Association of NLR with ESRD events among total CKD patients and stratified by stage of CKD

From: Neutrophil-to-lymphocyte ratio and incident end-stage renal disease in Chinese patients with chronic kidney disease: results from the Chinese Cohort Study of Chronic Kidney Disease (C-STRIDE)

NLR ratio

Model 1

Model 2

HR (95% CI)

HR (95% CI) 

Total CKD patients (n = 938)

 <  2.09

1.00 (Ref) 

1.00 (Ref) 

 ≥ 2.09

2.59 (1.72, 3.90)

1.16 (0.74, 1.81)

 p for trend

< 0.001

0.512

eGFR ≥ 60 mL/min (n = 360)

 < 2.09

1.00 (Ref) 

1.00 (Ref) 

 ≥ 2.09

1.77 (0.36, 8.87)

1.57 (0.21, 11.98)

 p for trend

0.485

0.663

30 ≤ eGFR < 60 mL/min (n = 345)

 < 2.09

1.00 (Ref) 

1.00 (Ref) 

 ≥ 2.09

0.98 (0.50, 1.92)

0.507 (0.23, 1.11)

 p for trend

0.95

0.089

15 ≤ eGFR < 30 mL/min (n = 233)

 < 2.09

1.00 (Ref) 

1.00 (Ref) 

 ≥ 2.09

2.11 (1.18, 3.76)

2.124 (1.10, 4.10)

 p for trend

0.012

0.025

  1. Model 1: Adjusted for age, gender
  2. Model 2: Model 1 + smoking, drinking, diabetes, hypertension, cardiovascular diseases, hyperuricemia, urine albumin/creatinine ratio, chronic kidney disease-mineral and bone disorder, hemoglobin, hyperlipidaemia, eGFR
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