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Table 1 Baseline demographic characteristics of participants of C-STRIDE Study according to NLR

From: Neutrophil-to-lymphocyte ratio and incident end-stage renal disease in Chinese patients with chronic kidney disease: results from the Chinese Cohort Study of Chronic Kidney Disease (C-STRIDE)

Variable Total (n = 938) NLR ≥ 2.09 (n = 520) NLR < 2.09 (n = 418) p value
Age (year)* 52.8 (14.14) 54.0 (14.48) 51.3 (13.58) 0.047**
Sex (men)$ 544 (58.00%) 304 (58.46%) 240 (57.42%) 0.747
Ever smoking$ 311 (34.2%) 180 (35.7%) 131 (32.3%) 0.276
Drinking ≥ 1 times per day$ 189 (21.00%) 101 (20.2%) 88 (22.0%) 0.510
BMI category (kg/m2)# 24.61 (22.04–27.34) 24.61 (22.01–27.42) 24.59 (21.99–27.31) 0.944
HGB (g/L)* 129.2 (22.78) 125.7 (23.00) 133.70 (21.71) 0.183
Systolic blood pressure (mmHg)* 127.51 (16.71) 129.91 (17.88) 124.92 (14.96) 0.537
Diastolic blood pressure (mmHg)* 80.13 (10.48) 81.11 (11.01) 79.08 (9.78) 0.918
Antihypertensive medications token in 2 weeks$ 507 (69.5%) 288 (74.0%) 219 (64.4%) 0.005**
Hypertension$ 538 (57.4%) 303 (58.3%) 235 (56.2%) < 0.001**
Uric acid (μmol/L)* 373.59 (132.08) 376.59 (136.42) 369.87 (126.55) 0.208
Serum triglycerides (mmol/L)# 1.66 (1.18–2.39) 1.61 (1.13–2.26) 1.79 (1.21–2.59) 0.021**
Hyperuricemia$ 407 (44.3%) 235 (46.2%) 172 (42.0%) 0.201
Total serum cholesterol (mmol/L)# 4.70 (4.01–5.57) 4.59 (3.94–5.39) 4.82 (4.12–5.89) 0.003**
LDL cholesterol (mmol/L)# 2.73 (2.22–3.40) 2.72 (2.20–3.36) 2.74 (2.23–3.48) 0.369
HDL cholesterol (mmol/L)# 1.12 (0.91–1.34) 1.12 (0.93–1.34) 1.12 (0.89–1.34) 0.729
Hyperlipidaemia$ 194 (26.6%) 98 (23.7%) 96 (30.5%) 0.039**
Cardiovascular disease$ 124 (13.40%) 81 (15.80%) 43 (10.40%) 0.017**
ACR (mg/g creatinine)# 343.05 (75.60–780.51) 420.50 (112.11–312.90) 290.01 (48.20–666.86) 0.000**
ACR group$ 814 447 367 0.006**
 1 < 30 mg/g 127 (15.6%) 56 (12.5%) 71 (19.3%)  
 2 = 30–299 mg/g 248 (30.5%) 130 (29.1%) 118 (32.2%)  
 3 ≥ 300 mg/g 439 (53.9%) 261 (58.4%) 178 (48.5%)  
sCa (mmol/L)* 2.22 (0.18) 2.23 (0.18) 2.22 (0.18) 0.735
sP (mmol/L)# 1.17 (1.05–1.31) 1.17 (1.04–1.31) 1.18 (1.05–1.32) 0.925
CKD-MBD$ 467 (54.6%) 274 (58.1%) 193 (50.3%) 0.023**
HCO3− (mmol/L)* 25.70 (3.78) 25.54 (3.99) 25.91 (3.49) 0.060
Diabetes$ 200 (23.8%) 135 (29.4%) 65 (17.1%) 0.000**
eGFR (mL/min/1.7 m2)* 57.22 (32.67) 48.73 (29.63) 67.78 (33.24) 0.000**
eGFR group$ 938    
 ≥ 60 mL/min/1.73 m2 360 (38.4%) 139 (26.7%) 221 (52.9%) 0.000**
 30–60 mL/min/1.73 m2 345 (36.8%) 212 (40.8%) 133 (31.8%)  
 15–30 mL/min/1.73 m2 233 (24.8%) 169 (32.5%) 64 (15.3%)  
High hs-CRP 146 (15.6%) 88 (16.9%) 58 (13.9%) 0.414
  1. The number of missing values for each variable: NLR 0, age 0, eGFR 0, sex 0, education 31, ever smoking 51, drinking ≥ 1 times per day 60, BMI category 211, anemia 0, systolic blood pressure 186, diatolic blood pressure 186, antihypertensive medications token in 2 weeks 334, uric acid 30, total serum cholesterol 338, serum triglycerides 347, LDL cholesterol 428, HDL cholesterol 425, CKD-MBD 0, cardiovascular disease 28, ACR 149, metabolic acidosis 589, pathogenesis chronic 0, high Hs-CRP 668
  2. The denominator of percentage is number of the variable
  3. * The variable is numerical and statistics is mean (standard deviation), p-value calculated based on T test
  4. #The variable is numerical and statistics is Median (Interquartile range), p-value calculated based on Wilcoxon test
  5. $The variable is character and statistics is frequency (percentage), p-value calculated based on Chi-square test
  6. ** Statistically significant at 0.05