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Fig. 3 | Journal of Translational Medicine

Fig. 3

From: Adiponectin regulates bone mass in AIS osteopenia via RANKL/OPG and IL6 pathway

Fig. 3

High IL6 and adipoR1 expression were observed in AIS cartilage. a Total RNA were extracted from three group. The relative expression level of TNF a, IL10, IL6, adiponectin, adipoR1, adipoR2 were detected by quantitative real-time PCR. The Y axis represents the fold change in transcript levels in three group. The control group was set to 1.0. b, c Protein level of IL6, adipoR1 were measured by western blotting. The Y axis represents the fold change and control were set to 1.0. d Representative images of immunohistochemical staining for adipoR1. e Quantitative analysis of the mean intensity for positively stained areas. Data are shown as the mean ± SD. One way ANOVA was use to tested, when p value > 0.05, there was no significant difference in all the groups; when p value < 0.05, then using bonferroni correction to test each two groups. *p < 0.0167 Bonferroni correction test between control and AIS concave. Bonferroni correction test between control and AIS convex. #p < 0.0167 Bonferroni correction test between AIS concave and AIS convex

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