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Table 1 Association between the plasma circRNA expression levels and clinicopathological characteristics of LUAD patients

From: A two-circular RNA signature as a noninvasive diagnostic biomarker for lung adenocarcinoma

Characteristics n = 153 Hsa_circ_0005962 Hsa_circ_0086414
Low (n = 43) High (n = 110) P value Low (n = 117) High (n = 36) P value
Age (years)
< 60 74 22 52 0.665 58 16 0.59
≥ 60 79 21 58   59 20  
Gender
Female 93 20 73 0.024 66 27 0.046
Male 60 23 37   51 9  
Smoking
No 99 23 76 0.097 72 27 0.089
Yes 53 19 34   45 8  
Tumor size
≤ 3 cm 99 25 74 0.907 75 24 0.956
> 3 cm 42 11 31   32 10  
Lymphatic metastasis
Negative 111 27 84 0.091 87 24 0.366
Positive 42 16 26   30 12  
Metastasis
M0 130 33 97 0.075 99 31 0.826
M1 23 10 13   18 5  
TNM stage
I 83 20 63 0.282 64 19 0.728
II and III and IV 68 21 47   51 17  
CEA
Negative 75 16 59 0.146 56 19 0.337
Positive 45 15 30   37 8  
EGFR mutation
Negative 26 10 16 0.287 25 1 0.001
Positive 42 11 31   25 17