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Fig. 1 | Journal of Translational Medicine

Fig. 1

From: A two-circular RNA signature as a noninvasive diagnostic biomarker for lung adenocarcinoma

Fig. 1

Circular RNA (circRNA) expression profiles of lung adenocarcinoma (LUAD) and matched nontumor tissues. a Volcano plot showing the differential expression of circRNAs between the tumor and normal groups. b Heatmap of the differential expression of the 23 selected LUAD-specific circRNAs in the GSE101586 dataset. c The expression of host genes of hsa_circ_0005962, hsa_circ_0003958, hsa_circ_0086414 and hsa_circ_0001936 in The Cancer Genome Atlas (TCGA)-LUAD dataset. d Overall survival analysis for the host genes of the four circRNAs in LUAD patients was performed using the Kaplan–Meier plotter. Log-rank tests were used to determine statistical significance. ****P < 0.0001

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