Fig. 1

Effect of different concentrations of A83-01 and different preconditioning strategies on PDLSC proliferation. A PDLSCs were treated with 0, 0.5, 1, 5, 10, 50 and 100 μM A83-01 for 48 h. The proliferation activity of PDLSCs was analysed with CCK8 kit. B Proliferation activity of preconditioned groups and a negative control group after 1,3, 5 and 7 days of cultivation in a medium only supplemented with 10% FBS. C–F Morphological observation of pre/non-preconditioned PDLSCs after 24 h of re-culture. (No matching letters (e.g.: a, b, c, d) above any two column charts represents a significant difference between these two groups (p < 0.05), while the appearance of any matching letters (e.g.: a, a) means that there is no significant difference among groups (p > 0.05). Data are expressed as mean ± SD)