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Fig. 7 | Journal of Translational Medicine

Fig. 7

From: High throughput sequencing of T-cell receptor repertoire using dry blood spots

Fig. 7

Schematics for the comparison of the methods for TCR repertoire discovery by using a DBS sample and peripheral blood sample. DBS provides a minimally invasive sample collection and convenient alternative to venipuncture. High quality RNA is extracted from DBS-based samples for future molecular amplification and analysis. The entire process of multiplex PCR amplification and library preparation of the immune repertoire is automated in a fully closed cassette, which allows for a less labor-intensive manual process, improves result consistency and prevents contamination amplicon within the laboratory environment

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