Table 1 The Gene Ontology (GO) terms enrichment for the co-expressed genes of the AF-related stroke
Gene/product | GO class (direct) | Evidence | Evidence with | Reference |
|---|---|---|---|---|
PDZK1IP1 | Integral component of membrane | IEA | UniProtKB-KW:KW-0812 | GO_REF:0000037 |
Extracellular exosome | IDA | Â | PMID:19056867 | |
ZNF566 | DNA binding | IEA | UniProtKB-KW:KW-0238 | GO_REF:0000037 |
Nucleus | IEA | UniProtKB-SubCell:SL-0191 | GO_REF:0000039 | |
Transcription, DNA-templated | IEA | UniProtKB-KW:KW-0804 | GO_REF:0000037 | |
Metal ion binding | IEA | UniProtKB-KW:KW-0479 | GO_REF:0000037 | |
ZFHX3 | Negative regulation of transcription from RNA polymerase II promoter | IGI | UniProtKB:P01104 | PMID:10318867 |
RNA polymerase II proximal promoter sequence-specific DNA binding | IDA | Â | PMID:7507206 | |
core promoter sequence-specific DNA binding | ISS | UniProtKB:Q61329 | GO_REF:0000024 | |
Transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | IC | GO:0000122/GO:0000978 | GO_REF:0000036 | |
Protein binding | IPI | UniProtKB:Q13761 | PMID:20599712 | |
Nucleus | TAS | Â | PMID:1719379 | |
PITX2 | Transcription regulatory region sequence-specific DNA binding | IDA | Â | PMID:9685346 |
Transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | IEA | UniProtKB:Q9R0W1 | GO_REF:0000107 | |
RNA polymerase II transcription coactivator activity | IDA | Â | PMID:9685346 | |
Branching involved in blood vessel morphogenesis | IEA | UniProtKB:P97474 | GO_REF:0000107 | |
Vasculogenesis | IEA | UniProtKB:P97474 | GO_REF:0000107 | |
In utero embryonic development | IEA | UniProtKB:P97474 | GO_REF:0000107 | |
Neuron migration | IEA | UniProtKB:P97474 | GO_REF:0000107 | |
Extraocular skeletal muscle development | IEA | UniProtKB:P97474 | GO_REF:0000107 |