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Table 1 The Gene Ontology (GO) terms enrichment for the co-expressed genes of the AF-related stroke
| Gene/product | GO class (direct) | Evidence | Evidence with | Reference |
|---|---|---|---|---|
| PDZK1IP1 | Integral component of membrane | IEA | UniProtKB-KW:KW-0812 | GO_REF:0000037 |
| Extracellular exosome | IDA | PMID:19056867 | ||
| ZNF566 | DNA binding | IEA | UniProtKB-KW:KW-0238 | GO_REF:0000037 |
| Nucleus | IEA | UniProtKB-SubCell:SL-0191 | GO_REF:0000039 | |
| Transcription, DNA-templated | IEA | UniProtKB-KW:KW-0804 | GO_REF:0000037 | |
| Metal ion binding | IEA | UniProtKB-KW:KW-0479 | GO_REF:0000037 | |
| ZFHX3 | Negative regulation of transcription from RNA polymerase II promoter | IGI | UniProtKB:P01104 | PMID:10318867 |
| RNA polymerase II proximal promoter sequence-specific DNA binding | IDA | PMID:7507206 | ||
| core promoter sequence-specific DNA binding | ISS | UniProtKB:Q61329 | GO_REF:0000024 | |
| Transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | IC | GO:0000122/GO:0000978 | GO_REF:0000036 | |
| Protein binding | IPI | UniProtKB:Q13761 | PMID:20599712 | |
| Nucleus | TAS | PMID:1719379 | ||
| PITX2 | Transcription regulatory region sequence-specific DNA binding | IDA | PMID:9685346 | |
| Transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | IEA | UniProtKB:Q9R0W1 | GO_REF:0000107 | |
| RNA polymerase II transcription coactivator activity | IDA | PMID:9685346 | ||
| Branching involved in blood vessel morphogenesis | IEA | UniProtKB:P97474 | GO_REF:0000107 | |
| Vasculogenesis | IEA | UniProtKB:P97474 | GO_REF:0000107 | |
| In utero embryonic development | IEA | UniProtKB:P97474 | GO_REF:0000107 | |
| Neuron migration | IEA | UniProtKB:P97474 | GO_REF:0000107 | |
| Extraocular skeletal muscle development | IEA | UniProtKB:P97474 | GO_REF:0000107 |
