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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Effectiveness of two different dose administration regimens of an IL-15 superagonist complex (ALT-803) in an orthotopic bladder cancer mouse model

Fig. 4

Treatment-related activation of peripheral immune cells in female mice bearing tumors. a Peripheral blood mononuclear cells collected 3 days after week 1 treatment were isolated and analyzed by flow cytometry for expression of CD3+, CD3+/CD8+, NKG2D+ and CD3+/NKG2D+ expression. SQ ALT-803 alone resulted in significant increase in CD8, NKG2D and CD3/NKG2D expression cells compared to PBS control. b Splenocytes collected 3 days after week 1 treatment were isolated and analyzed by flow cytometry for expression of CD3+, CD3+/CD8+, NKG2D+ and CD3+/NKG2D+ expression. SQ ALT-803 alone resulted in significant increase in CD3/NKG2D expressing cells compared to PBS control

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