TY - JOUR AU - Ranganathan, V. AU - Gracey, E. AU - Brown, M. A. AU - Inman, R. D. AU - Haroon, N. PY - 2017 DA - 2017// TI - Pathogenesis of ankylosing spondylitis—recent advances and future directions JO - Nat Rev Rheumatol VL - 13 UR - https://doi.org/10.1038/nrrheum.2017.56 DO - 10.1038/nrrheum.2017.56 ID - Ranganathan2017 ER - TY - JOUR AU - Smith, J. A. AU - Colbert, R. A. PY - 2014 DA - 2014// TI - Review: the interleukin-23/interleukin-17 axis in spondyloarthritis pathogenesis: Th17 and beyond JO - Arthritis Rheumatol. VL - 66 UR - https://doi.org/10.1002/art.38291 DO - 10.1002/art.38291 ID - Smith2014 ER - TY - JOUR AU - Lubberts, E. PY - 2015 DA - 2015// TI - The IL-23-IL-17 axis in inflammatory arthritis JO - Nat Rev Rheumatol VL - 11 UR - https://doi.org/10.1038/nrrheum.2015.53 DO - 10.1038/nrrheum.2015.53 ID - Lubberts2015 ER - TY - JOUR AU - Baeten, D. AU - Sieper, J. AU - Braun, J. AU - Baraliakos, X. AU - Dougados, M. AU - Emery, P. PY - 2015 DA - 2015// TI - Secukinumab, an Interleukin-17A inhibitor, in ankylosing spondylitis JO - N Engl J Med VL - 373 UR - https://doi.org/10.1056/NEJMoa1505066 DO - 10.1056/NEJMoa1505066 ID - Baeten2015 ER - TY - JOUR AU - Marzo-Ortega, H. AU - Sieper, J. AU - Kivitz, A. AU - Blanco, R. AU - Cohen, M. AU - Martin, R. PY - 2017 DA - 2017// TI - Secukinumab and sustained improvement in signs and symptoms of patients with active ankylosing spondylitis through two years: results from a phase III study JO - Arthritis Care Res (Hoboken). VL - 69 UR - https://doi.org/10.1002/acr.23233 DO - 10.1002/acr.23233 ID - Marzo-Ortega2017 ER - TY - JOUR AU - Zhang, L. AU - Li, Y. G. AU - Li, Y. H. AU - Qi, L. AU - Liu, X. G. AU - Yuan, C. Z. PY - 2012 DA - 2012// TI - Increased frequencies of Th22 cells as well as Th17 cells in the peripheral blood of patients with ankylosing spondylitis and rheumatoid arthritis JO - PLoS ONE VL - 7 UR - https://doi.org/10.1371/journal.pone.0031000 DO - 10.1371/journal.pone.0031000 ID - Zhang2012 ER - TY - JOUR AU - Shen, H. AU - Goodall, J. C. AU - Hill Gaston, J. S. PY - 2009 DA - 2009// TI - Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis JO - Arthritis Rheum VL - 60 UR - https://doi.org/10.1002/art.24568 DO - 10.1002/art.24568 ID - Shen2009 ER - TY - JOUR AU - Grant, C. R. AU - Liberal, R. AU - Mieli-Vergani, G. AU - Vergani, D. AU - Longhi, M. S. PY - 2015 DA - 2015// TI - Regulatory T-cells in autoimmune diseases: challenges, controversies and-yet-unanswered questions JO - Autoimmun Rev VL - 14 UR - https://doi.org/10.1016/j.autrev.2014.10.012 DO - 10.1016/j.autrev.2014.10.012 ID - Grant2015 ER - TY - JOUR AU - Ji, W. AU - Li, H. AU - Gao, F. AU - Chen, Y. AU - Zhong, L. AU - Wang, D. PY - 2014 DA - 2014// TI - Effects of Tripterygium glycosides on interleukin-17 and CD4(+)CD25(+)CD127(low) regulatory T-cell expression in the peripheral blood of patients with ankylosing spondylitis JO - Biomed Rep. VL - 2 UR - https://doi.org/10.3892/br.2014.262 DO - 10.3892/br.2014.262 ID - Ji2014 ER - TY - JOUR AU - Duan, Z. AU - Gui, Y. AU - Li, C. AU - Lin, J. AU - Gober, H. J. AU - Qin, J. PY - 2017 DA - 2017// TI - The immune dysfunction in ankylosing spondylitis patients JO - Biosci Trends. VL - 11 UR - https://doi.org/10.5582/bst.2016.01171 DO - 10.5582/bst.2016.01171 ID - Duan2017 ER - TY - JOUR AU - Bidad, K. AU - Salehi, E. AU - Jamshidi, A. AU - Saboor-Yaraghi, A. A. AU - Oraei, M. AU - Meysamie, A. PY - 2013 DA - 2013// TI - Effect of all-transretinoic acid on Th17 and T regulatory cell subsets in patients with ankylosing spondylitis JO - J Rheumatol VL - 40 UR - https://doi.org/10.3899/jrheum.121100 DO - 10.3899/jrheum.121100 ID - Bidad2013 ER - TY - JOUR AU - Min, H. K. AU - Kim, J. K. AU - Lee, S. Y. AU - Kim, E. K. AU - Lee, S. H. AU - Lee, J. PY - 2016 DA - 2016// TI - Rebamipide prevents peripheral arthritis and intestinal inflammation by reciprocally regulating Th17/Treg cell imbalance in mice with curdlan-induced spondyloarthritis JO - J Transl Med. VL - 14 UR - https://doi.org/10.1186/s12967-016-0942-5 DO - 10.1186/s12967-016-0942-5 ID - Min2016 ER - TY - JOUR AU - O’Shea, J. J. AU - Lahesmaa, R. AU - Vahedi, G. AU - Laurence, A. AU - Kanno, Y. PY - 2011 DA - 2011// TI - Genomic views of STAT function in CD4 + T helper cell differentiation JO - Nat Rev Immunol VL - 11 UR - https://doi.org/10.1038/nri2958 DO - 10.1038/nri2958 ID - O’Shea2011 ER - TY - JOUR AU - Dong, C. PY - 2008 DA - 2008// TI - TH17 cells in development: an updated view of their molecular identity and genetic programming JO - Nat Rev Immunol VL - 8 UR - https://doi.org/10.1038/nri2295 DO - 10.1038/nri2295 ID - Dong2008 ER - TY - JOUR AU - Miossec, P. AU - Korn, T. AU - Kuchroo, V. K. PY - 2009 DA - 2009// TI - Interleukin-17 and type 17 helper T cells JO - N Engl J Med VL - 361 UR - https://doi.org/10.1056/NEJMra0707449 DO - 10.1056/NEJMra0707449 ID - Miossec2009 ER - TY - JOUR AU - Lee, S. H. AU - Moon, S. J. AU - Park, M. J. AU - Kim, E. K. AU - Moon, Y. M. AU - Cho, M. L. PY - 2014 DA - 2014// TI - PIAS3 suppresses acute graft-versus-host disease by modulating effector T and B cell subsets through inhibition of STAT3 activation JO - Immunol Lett VL - 160 UR - https://doi.org/10.1016/j.imlet.2014.03.014 DO - 10.1016/j.imlet.2014.03.014 ID - Lee2014 ER - TY - JOUR AU - Tang, X. AU - Yin, K. AU - Zhu, H. AU - Tian, J. AU - Shen, D. AU - Yi, L. PY - 2016 DA - 2016// TI - Correlation between the expression of microRNA-301a-3p and the proportion of Th17 cells in patients with rheumatoid arthritis JO - Inflammation. VL - 39 UR - https://doi.org/10.1007/s10753-016-0304-8 DO - 10.1007/s10753-016-0304-8 ID - Tang2016 ER - TY - JOUR AU - Ruutu, M. AU - Thomas, G. AU - Steck, R. AU - Degli-Esposti, M. A. AU - Zinkernagel, M. S. AU - Alexander, K. PY - 2012 DA - 2012// TI - beta-glucan triggers spondylarthritis and Crohn’s disease-like ileitis in SKG mice JO - Arthritis Rheum VL - 64 UR - https://doi.org/10.1002/art.34423 DO - 10.1002/art.34423 ID - Ruutu2012 ER - TY - JOUR AU - Han, E. S. AU - Oh, J. Y. AU - Park, H. J. PY - 2011 DA - 2011// TI - Cordyceps militaris extract suppresses dextran sodium sulfate-induced acute colitis in mice and production of inflammatory mediators from macrophages and mast cells JO - J Ethnopharmacol VL - 134 UR - https://doi.org/10.1016/j.jep.2011.01.022 DO - 10.1016/j.jep.2011.01.022 ID - Han2011 ER - TY - JOUR AU - Burns, R. C. AU - Rivera-Nieves, J. AU - Moskaluk, C. A. AU - Matsumoto, S. AU - Cominelli, F. AU - Ley, K. PY - 2001 DA - 2001// TI - Antibody blockade of ICAM-1 and VCAM-1 ameliorates inflammation in the SAMP-1/Yit adoptive transfer model of Crohn’s disease in mice JO - Gastroenterology VL - 121 UR - https://doi.org/10.1053/gast.2001.29568 DO - 10.1053/gast.2001.29568 ID - Burns2001 ER - TY - JOUR AU - Heijde, D. AU - Ramiro, S. AU - Landewe, R. AU - Baraliakos, X. AU - Bosch, F. AU - Sepriano, A. PY - 2017 DA - 2017// TI - 2016 update of the ASAS-EULAR management recommendations for axial spondyloarthritis JO - Ann Rheum Dis VL - 76 UR - https://doi.org/10.1136/annrheumdis-2016-210770 DO - 10.1136/annrheumdis-2016-210770 ID - Heijde2017 ER - TY - JOUR AU - Yang, X. P. AU - Ghoreschi, K. AU - Steward-Tharp, S. M. AU - Rodriguez-Canales, J. AU - Zhu, J. AU - Grainger, J. R. PY - 2011 DA - 2011// TI - Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5 JO - Nat Immunol VL - 12 UR - https://doi.org/10.1038/ni.1995 DO - 10.1038/ni.1995 ID - Yang2011 ER - TY - JOUR AU - Appel, H. AU - Maier, R. AU - Wu, P. AU - Scheer, R. AU - Hempfing, A. AU - Kayser, R. PY - 2011 DA - 2011// TI - Analysis of IL-17(+) cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response JO - Arthritis Res Ther. VL - 13 UR - https://doi.org/10.1186/ar3370 DO - 10.1186/ar3370 ID - Appel2011 ER - TY - JOUR AU - Noordenbos, T. AU - Yeremenko, N. AU - Gofita, I. AU - Sande, M. AU - Tak, P. P. AU - Canete, J. D. PY - 2012 DA - 2012// TI - Interleukin-17-positive mast cells contribute to synovial inflammation in spondylarthritis JO - Arthritis Rheum VL - 64 UR - https://doi.org/10.1002/art.33396 DO - 10.1002/art.33396 ID - Noordenbos2012 ER - TY - JOUR AU - Gracey, E. AU - Qaiyum, Z. AU - Almaghlouth, I. AU - Lawson, D. AU - Karki, S. AU - Avvaru, N. PY - 2016 DA - 2016// TI - IL-7 primes IL-17 in mucosal-associated invariant T (MAIT) cells, which contribute to the Th17-axis in ankylosing spondylitis JO - Ann Rheum Dis VL - 75 UR - https://doi.org/10.1136/annrheumdis-2015-208902 DO - 10.1136/annrheumdis-2015-208902 ID - Gracey2016 ER - TY - JOUR AU - Jandus, C. AU - Bioley, G. AU - Rivals, J. P. AU - Dudler, J. AU - Speiser, D. AU - Romero, P. PY - 2008 DA - 2008// TI - Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides JO - Arthritis Rheum VL - 58 UR - https://doi.org/10.1002/art.23655 DO - 10.1002/art.23655 ID - Jandus2008 ER - TY - JOUR AU - Jansen, D. T. AU - Hameetman, M. AU - Bergen, J. AU - Huizinga, T. W. AU - Heijde, D. AU - Toes, R. E. PY - 2015 DA - 2015// TI - IL-17-producing CD4 + T cells are increased in early, active axial spondyloarthritis including patients without imaging abnormalities JO - Rheumatology (Oxford) VL - 54 UR - https://doi.org/10.1093/rheumatology/keu382 DO - 10.1093/rheumatology/keu382 ID - Jansen2015 ER - TY - JOUR AU - Xueyi, L. AU - Lina, C. AU - Zhenbiao, W. AU - Qing, H. AU - Qiang, L. AU - Zhu, P. PY - 2013 DA - 2013// TI - Levels of circulating Th17 cells and regulatory T cells in ankylosing spondylitis patients with an inadequate response to anti-TNF-alpha therapy JO - J Clin Immunol VL - 33 UR - https://doi.org/10.1007/s10875-012-9774-0 DO - 10.1007/s10875-012-9774-0 ID - Xueyi2013 ER - TY - JOUR AU - Wilson, R. P. AU - Ives, M. L. AU - Rao, G. AU - Lau, A. AU - Payne, K. AU - Kobayashi, M. PY - 2015 DA - 2015// TI - STAT3 is a critical cell-intrinsic regulator of human unconventional T cell numbers and function JO - J Exp Med VL - 212 UR - https://doi.org/10.1084/jem.20141992 DO - 10.1084/jem.20141992 ID - Wilson2015 ER - TY - JOUR AU - Tam, L. S. AU - Gu, J. AU - Yu, D. PY - 2010 DA - 2010// TI - Pathogenesis of ankylosing spondylitis JO - Nat Rev Rheumatol VL - 6 UR - https://doi.org/10.1038/nrrheum.2010.79 DO - 10.1038/nrrheum.2010.79 ID - Tam2010 ER - TY - JOUR AU - Haroon, N. AU - Inman, R. D. AU - Learch, T. J. AU - Weisman, M. H. AU - Lee, M. AU - Rahbar, M. H. PY - 2013 DA - 2013// TI - The impact of tumor necrosis factor alpha inhibitors on radiographic progression in ankylosing spondylitis JO - Arthritis Rheum VL - 65 ID - Haroon2013 ER - TY - JOUR AU - Baraliakos, X. AU - Haibel, H. AU - Listing, J. AU - Sieper, J. AU - Braun, J. PY - 2014 DA - 2014// TI - Continuous long-term anti-TNF therapy does not lead to an increase in the rate of new bone formation over 8 years in patients with ankylosing spondylitis JO - Ann Rheum Dis VL - 73 UR - https://doi.org/10.1136/annrheumdis-2012-202698 DO - 10.1136/annrheumdis-2012-202698 ID - Baraliakos2014 ER - TY - JOUR AU - Molnar, C. AU - Scherer, A. AU - Baraliakos, X. AU - Hooge, M. AU - Micheroli, R. AU - Exer, P. PY - 2018 DA - 2018// TI - TNF blockers inhibit spinal radiographic progression in ankylosing spondylitis by reducing disease activity: results from the Swiss Clinical Quality Management cohort JO - Ann Rheum Dis VL - 77 UR - https://doi.org/10.1136/annrheumdis-2017-211544 DO - 10.1136/annrheumdis-2017-211544 ID - Molnar2018 ER - TY - JOUR AU - Baraliakos, X. AU - Heldmann, F. AU - Callhoff, J. AU - Listing, J. AU - Appelboom, T. AU - Brandt, J. PY - 2014 DA - 2014// TI - Which spinal lesions are associated with new bone formation in patients with ankylosing spondylitis treated with anti-TNF agents? A long-term observational study using MRI and conventional radiography JO - Ann Rheum Dis VL - 73 UR - https://doi.org/10.1136/annrheumdis-2013-203425 DO - 10.1136/annrheumdis-2013-203425 ID - Baraliakos2014 ER - TY - JOUR AU - Magrey, M. N. AU - Khan, M. A. PY - 2017 DA - 2017// TI - The paradox of bone formation and bone loss in ankylosing spondylitis: evolving new concepts of bone formation and future trends in management JO - Curr Rheumatol Rep VL - 19 UR - https://doi.org/10.1007/s11926-017-0644-x DO - 10.1007/s11926-017-0644-x ID - Magrey2017 ER - TY - JOUR AU - Xie, Z. AU - Wang, P. AU - Li, Y. AU - Deng, W. AU - Zhang, X. AU - Su, H. PY - 2016 DA - 2016// TI - Imbalance between bone morphogenetic protein 2 and noggin induces abnormal osteogenic differentiation of mesenchymal stem cells in ankylosing spondylitis JO - Arthritis Rheumatol. VL - 68 UR - https://doi.org/10.1002/art.39433 DO - 10.1002/art.39433 ID - Xie2016 ER - TY - JOUR AU - Chen, H. A. AU - Chen, C. H. AU - Lin, Y. J. AU - Chen, P. C. AU - Chen, W. S. AU - Lu, C. L. PY - 2010 DA - 2010// TI - Association of bone morphogenetic proteins with spinal fusion in ankylosing spondylitis JO - J Rheumatol VL - 37 UR - https://doi.org/10.3899/jrheum.100200 DO - 10.3899/jrheum.100200 ID - Chen2010 ER - TY - JOUR AU - Chen, M. H. AU - Chen, H. A. AU - Chen, W. S. AU - Chen, M. H. AU - Tsai, C. Y. AU - Chou, C. T. PY - 2015 DA - 2015// TI - Upregulation of BMP-2 expression in peripheral blood mononuclear cells by proinflammatory cytokines and radiographic progression in ankylosing spondylitis JO - Mod Rheumatol VL - 25 UR - https://doi.org/10.3109/14397595.2015.1029221 DO - 10.3109/14397595.2015.1029221 ID - Chen2015 ER -