Fig. 6

Detection of serum neutralizing antibodies. Humoral response was determined by direct ELISA of serum NAbs (IgG anti-hAd), a Exp.1, b Exp.2. Group’s means are represented as horizontal bars. (EXP.1 n = 6 mice/group; EXP.2 n = 4 mice for saline IV, MBs IV, hAd-GFP IV, MBs (hAd-GFP) IV groups and n = 3 mice for MBs(hAd-GFP) + US IV and hAd-GFP IT. Data are analyzed by two way ANOVA and Tukey’s post-test, *p < 0.05, **p < 0.01, ***p < 0.001)