Fig. 6
From: MicroRNA-regulated pathways of flow-stimulated angiogenesis and vascular remodeling in vivo
Immunohistochemical staining for CXCL2 and IL1A. Immunohistochemical analysis of C–X–C chemokine ligand 2 (CXCL2) (a–c) and interleukin-1 alpha (IL1A) protein expression (d–f) in AV shunt and control vein (Co) cross sections show a significant increase in the expression of both proteins in the endothelial cells of AV shunts on postoperative day (POD) 5 (a, d) and an even stronger expression on POD 15 (c, f) compared to control veins (a, d). The black Indian ink filling the vessel lumen (*) appears detached from the endothelium in some sections due to cutting artifacts