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Table 3 Possible risk factors for graft failure

From: Risk factors influencing survival of acellular porcine corneal stroma in infectious keratitis: a prospective clinical study

ParameterTherapeutic success (n = 27)Graft failure (n = 12)PType of statistical test
Indication for graft0.046Weighted log-rank testb
 Nonviral24 (75.0%)8 (25.0%)
 Herpetic3 (42.9%)4 (57.1%)
Mean lesion sizea (mm)4.81 ± 1.17 (2.78–7.34)5.92 ± 1.00 (3.39–7.18)0.007t-test
Mean graft size (mm)7.59 ± 0.21 (7.25–8.00)7.95 ± 0.38 (7.25–8.5)< 0.001t-test
Graft size group< 0.001Log-rank test
 < 8.025 (83.3%)5 (16.7%)
 ≥ 8.02 (22.2%)7 (77.8%)
Preoperative sterile hypopyon0.198Log-rank test
 Absence23 (65.7%)12 (34.3%)
 Presence4 (100%)0 (0%)
  1. aLesion size reported as the equivalent circular diameter
  2. bBecause of the presence of nonproportional hazards, the weighted log-rank test was used to compare the survival distributions between nonviral keratitis and herpetic keratitis groups. Fleming–Harrington weights of P = 0, q = 0.5 were set to emphasize differences occurring later in time