From: Malignant transformation of oral leukoplakia is associated with macrophage polarization
 | AUC | COP | No. of cases | + | − | % pos. cases (%) | p-value χ2 test | Sensitivity | Specificity | Positive predictive value | Negative predictive value |
---|---|---|---|---|---|---|---|---|---|---|---|
CD68 epithelial | 0.660 | 2.92 | 103 | 70 | 33 | Â | 0.003 | 58.6% | 72.7% | 0.820 | 0.453 |
 Transforming OLP |  |  | 50 | 41 | 9 | 82.0 |  |  |  |  |  |
 Non-transforming OLP |  |  | 53 | 29 | 24 | 54.7 |  |  |  |  |  |
CD68 subepithelial | 0.773 | 95.18 | 99 | 50 | 49 |  | < 0.001 | 72.0% | 73.5% | 0.735 | 0.720 |
 Transforming OLP |  |  | 49 | 36 | 13 | 73.5 |  |  |  |  |  |
 Non-transforming OLP |  |  | 50 | 14 | 36 | 28.0 |  |  |  |  |  |
CD163 epithelial | 0.724 | 1.12 | 96 | 63 | 33 | Â | 0.010 | 55.6% | 72.7% | 0.795 | 0.462 |
 Transforming OLP |  |  | 44 | 35 | 9 | 79.5 |  |  |  |  |  |
 Non-transforming OLP |  |  | 52 | 28 | 24 | 53.8 |  |  |  |  |  |