Fig. 2
From: The important role of connexin 43 in subarachnoid hemorrhage-induced cerebral vasospasm
PKC inhibitors decrease the gap junction intercellular communication induced by OxyHb in BASMCs. a Representative photomicrographs show fluorescence images of one microinjected cell and its adjacent cells containing the dye tracer after injection of Lucifer yellow in each group. The injected cell is marked with a black arrow, neighboring cells which show dye transfer are marked with white asterisks; Scale bar = 5 μm. Under normal conditions 9.88 ± 2.59 cells were coupled, while in OxyHb-only group the number of coupled cells increased to 18.5 ± 3.12. After pre-treatment of CHE and GF, the coupled cells decreased significantly as 14.13 ± 2.70 and 13.88 ± 2.42. b Quantitative results of (a). Data represent the mean ± SEM, *P<0.01 vs. normal group, #P<0.01 vs. OxyHb-only group, n = 8. The fluorescence images and corresponding brightfield images in each group are presented in Additional file 1: Fig. S3