Fig. 5

ELISA assay for CRP and SAA. a ELISA assay for CRP and SAA on serum from healthy volunteers (HV) and ERA patients at time T0 and after 12 months of treatment (T12). The log transformation was applied to concentration values of CRP and SAA. Scatter dot plots represent the M ± SD. ^###P-value ≤ 0.001 (HV vs RA; unpaired t-test); ***P-value ≤ 0.001 (T0 vs T12; paired t-test). b Variation of CRP and SAA in good (R) and non (NR) responders. ^#P-value ≤ 0.05; ^###P-value ≤ 0.001 (HV vs RA; unpaired t-test); ***P-value ≤ 0.001 (T0 vs T12; paired t-test)