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Table 4 Multivariable Cox proportional hazard model predicting BCR by adding 4 markers to SOC

From: Multi-omic serum biomarkers for prognosis of disease progression in prostate cancer

Variable

HR

95% CI

P value

Pathological T stage (T3 vs T2)

2.81

1.49–5.30

0.001

Gleason sum (4 + 3/8 − 10 vs 3 + 3/3 + 4)

5.57

3.25–9.56

< 0.001

Surgical margin (Pos vs neg)

1.27

0.62–2.57

0.511

PA-18:0–22:0 (Low vs high)

2.49

1.30–4.79

0.006

Apolipoprotein A-IV (High vs low)

2.21

1.15–4.24

0.017

Tenascin C (High vs low)

0.99

0.56–1.73

0.966

1-Methyladenosine (high vs low)

2.11

1.14–3.92

0.017

  1. The statistically significant P values (P < 0.05) are given in italics
  2. SOC standard of care, HR hazards ratio, CI confidence interval