Fig. 2

Volcano plots depict the top analytes from serum samples of prostate cancer patients with BCR, run through different mass spectrometry platforms for abundance of a metabolites, b proteins, c structural lipids and d signaling lipids. Each dot in the plot represents an analyte. The X-axis represents the fold change of the analytes (log2 scale); the Y-axis representing the P-values in − log10 scale. The color bar represents the number of analytes that had a fold-change and P-value in that range. For metabolites: 17 had an unadjusted P ≤ 0.05. For proteins: 13 had an unadjusted P ≤ 0.05. For structural lipids: 56 had an unadjusted P ≤ 0.05. For signaling lipids: 2 had an unadjusted P ≤ 0.05