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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Upregulation of mitotic bookmarking factors during enhanced proliferation of human stromal cells in human platelet lysate

Fig. 4

Upregulation of mRNA expression of distinct transcription factors in pHPL-media. a Heat map depicting the fold change mRNA expression of NANOG, SOX2, KLF4, cMYC and OCT4 in stromal cells cultivated in pHPL-, pHPLS- and mcpHPL-based medium with red color indicating up- and blue color downregulation compared to FBS medium. b mRNA expression of selected transcription and mitotic bookmarking factors in BM-, WAT- and UC-derived stromal cells cultured in pHPL-based media (summarized as red/orange/green bar) compared to FBS (blue bar). Data shown are mean fold change values of three individual donors for each tissue source measured in duplicates (*p < 0.05, **p < 0.01)

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