Fig. 7

The effects of ITGB1 on cell cycle of TCs treated with PI3K inhibitors and TGFβ1. a–d Cell cycle analysis of HS173 (PI3K/p110α inhibitor) in TGFβ1-induced TC^ITGB1+ by flowcytometry. e–f. Cell cycle analysis of GDC0941 (pan-PI3K inhibitor) in TGFβ1-induced TC^ITGB1+ by flowcytometry. g–h Cell cycle analysis of Enzastaurin (PI3K/PKC inhibitor) in TGFβ1-induced TC^ITGB1+ by flowcytometry. i–j Cell cycle analysis of SB216763 (GSK-3 inhibitor) in TGFβ1-induced TC^ITGB1+ by flowcytometry, n = 3–6, * stand for p values less than 0.05, as compared with TGFβ1-induced TC ^ITGB1+, ^# stand for p values less than 0.05, as TC^ITGB1− treated with PI3K inhibitors and TGFβ1compared with TC ^ITGB1+ treated with PI3K inhibitors and TGFβ1. **   stand for p values less than 0.05, as compared with TC ^ITGB1+, ^##  stand for p values less than 0.05, as compared with TC ^ITGB1−, ***stand for p values less than 0.05, as compared with  TGFβ1-induced TC ^ITGB1+