Fig. 9

Vital DEPs validation in patients with AIH. a Representative H&E staining of liver tissue section from a patient with AIH. b Plasma from patients with AIH, hepatitis B patients, hepatitis C patients, and healthy people were collected and the SAA1 expression levels in the plasma were detected by ELISA (n = 30, ***P < 0.001 vs. Control). c Immunohistochemical staining of human liver tissues for SAA1 detection are shown (n = 3, ×200 magnification). d Box plot of plasma SAA1 level in patients with AIH from different inflammation grades (n = 7 for G0–G1, n = 14 for G2, n = 8 for G3–G4, ^#Kruskal–Wallis nonparametric test *Mann–Whitney test). The line through the middle of each box represents the median. The length of the box represents the level range. e Box plot of plasma SAA1 level in patients with AIH from different fibrosis stages (n = 14 for S0–S1, n = 8 for S2, n = 7 for S3–S4, ^#Kruskal–Wallis nonparametric test *Mann–Whitney test)