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Table 2 AUC, PPV, NPV, sensitivity and specificity for PMN elastae in patients with myositis

From: Correlation of PMN elastase and PMN elastase-to-neutrophil ratio with disease activity in patients with myositis

 

IIMs

DM

PM

PMN elastase

CK

ENR

PMN elastase

CK

ENR

PMN elastase

CK

ENR

AUC

(95% CI)

0.90***

(0.83–0.97)

0.72**

(0.61–0.84)

0.96***

(0.92–1.0)

0.90***

(0.82–0.98)

0.70*

(0.57–0.83)

0.96***

(0.91–1.0)

0.88*

(0.65–1.0)

0.80*

(0.56–1.0)

1.0**

(1.0–1.0)

Cut off value

(ng/mL)

1632.4

84.8

329.0

1632.4

107.9

329.0

1632.4

107.9

329.0

PPV

1

0.89

0.98

1

1

0.98

1

1

1

NPV

0.77

0.59

0.85

0.68

0.44

0.89

0.78

0.58

1

Sensitivity (%)

79

56

88

80

42.9

94

80

43

94

Specificity (%)

100

90

97

100

100

96

100

100

96

  1. AUC area under the curve, PPV positive predictive value, NPV negative predictive value; 95% CI 95% confidence interval, ENR PMN elastase-to-netrophil ratio
  2. * P < 0.05 for the area under the curve; **P < 0.01 for the area under the curve; ***P < 0.001 for the area under the curve
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Journal of Translational Medicine

ISSN: 1479-5876

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