Fig. 1

Microglia activation following SLE-serum, healthy-serum or ACSF injection. Microscopic images of the Iba-1 immunolabelled cortical (a, c and e) and hippocampal (b, d and f) sections depicting morphological transformation of microglia after injection of ACSF (a and b), healthy-serum (c and d) and SLE-serum (e and f). The upper-left square represents the amplification of the middle square i.e. from resting state in ACSF and healthy-serum injection to activated phenotype in SLE-serum injection