TY - JOUR AU - Fitzmaurice, C. AU - Abate, D. AU - Abbasi, N. AU - Abbastabar, H. AU - Abd-Allah, F. AU - Abdel-Rahman, O. PY - 2019 DA - 2019// TI - Global, regional, and national cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life-years for 29 cancer groups, 1990 to 2017: a systematic analysis for the global burden of disease study JO - JAMA Oncol. UR - https://doi.org/10.1001/jamaoncol.2019.2996 DO - 10.1001/jamaoncol.2019.2996 ID - Fitzmaurice2019 ER - TY - JOUR AU - Siegel, R. L. AU - Miller, K. D. AU - Jemal, A. PY - 2018 DA - 2018// TI - Cancer statistics JO - CA cancer J Clin. VL - 68 UR - https://doi.org/10.3322/caac.21442 DO - 10.3322/caac.21442 ID - Siegel2018 ER - TY - JOUR AU - Miller, V. A. AU - Hirsh, V. AU - Cadranel, J. AU - Chen, Y. AU - Park, K. AU - Kim, S. W. PY - 2012 DA - 2012// TI - Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-Lung 1): a phase 2b/3 randomised trial JO - Lancet Oncol. VL - 13 UR - https://doi.org/10.1016/S1470-2045(12)70087-6 DO - 10.1016/S1470-2045(12)70087-6 ID - Miller2012 ER - TY - JOUR AU - Lawrence, R. E. AU - Salgia, R. PY - 2010 DA - 2010// TI - MET molecular mechanisms and therapies in lung cancer JO - Cell Adh Migr. VL - 4 UR - https://doi.org/10.4161/cam.4.1.10973 DO - 10.4161/cam.4.1.10973 ID - Lawrence2010 ER - TY - JOUR AU - Hirsch, F. R. AU - Scagliotti, G. V. AU - Mulshine, J. L. PY - 2017 DA - 2017// TI - Lung cancer: current therapies and new targeted treatments JO - Lancet VL - 389 UR - https://doi.org/10.1016/S0140-6736(16)30958-8 DO - 10.1016/S0140-6736(16)30958-8 ID - Hirsch2017 ER - TY - JOUR AU - Chu, B. B. AU - Wang, J. AU - Wang, Y. AU - Yang, G. PY - 2015 DA - 2015// TI - Knockdown of PKM2 induces apoptosis and autophagy in human A549 alveolar adenocarcinoma cells JO - Mol Med Rep. VL - 12 UR - https://doi.org/10.3892/mmr.2015.3943 DO - 10.3892/mmr.2015.3943 ID - Chu2015 ER - TY - JOUR AU - Liu, Y. AU - Yuan, X. AU - Li, W. AU - Cao, Q. AU - Shu, Y. PY - 2016 DA - 2016// TI - Aspirin-triggered resolvin D1 inhibits TGF-β1-induced EMT through the inhibition of the mTOR pathway by reducing the expression of PKM2 and is closely linked to oxidative stress JO - Int J Mol Med. VL - 38 UR - https://doi.org/10.3892/ijmm.2016.2721 DO - 10.3892/ijmm.2016.2721 ID - Liu2016 ER - TY - JOUR AU - Yan, Y. L. AU - Xu, Z. AU - Qian, L. AU - Zeng, S. AU - Zhou, Y. AU - Chen, X. PY - 2019 DA - 2019// TI - Identification of CAV1 and DCN as potential predictive biomarkers for lung adenocarcinoma JO - Am J Physiol Lung Cell Mol Physiol VL - 316 UR - https://doi.org/10.1152/ajplung.00364.2018 DO - 10.1152/ajplung.00364.2018 ID - Yan2019 ER - TY - JOUR AU - Xu, L. AU - Lu, C. AU - Huang, Y. AU - Zhou, Z. AU - Wang, X. AU - Liu, C. PY - 2018 DA - 2018// TI - SPINK1 promotes cell growth and metastasis of lung adenocarcinoma and acts as a novel prognostic biomarker JO - BMB Rep. VL - 51 UR - https://doi.org/10.5483/BMBRep.2018.51.12.205 DO - 10.5483/BMBRep.2018.51.12.205 ID - Xu2018 ER - TY - JOUR AU - Feng, M. AU - Zhao, J. AU - Wang, L. AU - Liu, J. PY - 2018 DA - 2018// TI - Upregulated expression of serum exosomal micrornas as diagnostic biomarkers of lung adenocarcinoma JO - Ann Clin Lab Sci VL - 48 ID - Feng2018 ER - TY - JOUR AU - Liu, S. AU - Miao, C. AU - Liu, J. AU - Wang, C. AU - Liu, X. PY - 2018 DA - 2018// TI - Four differentially methylated gene pairs to predict the prognosis for early stage hepatocellular carcinoma patients JO - J Cell Physiol VL - 233 UR - https://doi.org/10.1002/jcp.26256 DO - 10.1002/jcp.26256 ID - Liu2018 ER - TY - JOUR AU - Chen, Y. AU - Ge, G. AU - Qi, C. AU - Wang, H. AU - Wang, H. L. AU - Li, L. PY - 2018 DA - 2018// TI - A five-gene signature may predict sunitinib sensitivity and serve as prognostic biomarkers for renal cell carcinoma JO - J Cell Physiol VL - 233 UR - https://doi.org/10.1002/jcp.26441 DO - 10.1002/jcp.26441 ID - Chen2018 ER - TY - JOUR AU - DeSantis, C. AU - Ma, J. AU - Bryan, L. AU - Jemal, A. PY - 2014 DA - 2014// TI - Breast cancer statistics, 2013 JO - CA Cancer J Clin VL - 64 UR - https://doi.org/10.3322/caac.21203 DO - 10.3322/caac.21203 ID - DeSantis2014 ER - TY - JOUR AU - Subramanian, A. AU - Tamayo, P. AU - Mootha, V. K. AU - Mukherjee, S. AU - Ebert, B. L. AU - Gillette, M. A. PY - 2005 DA - 2005// TI - Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles JO - Proc Natl Acad Sci USA VL - 102 UR - https://doi.org/10.1073/pnas.0506580102 DO - 10.1073/pnas.0506580102 ID - Subramanian2005 ER - TY - JOUR AU - Zhang, M. AU - Liu, X. AU - Li, H. AU - Li, R. AU - Liu, X. AU - Qu, Y. PY - 2018 DA - 2018// TI - Elevated mRNA Levels of AURKA, CDC20 and TPX2 are associated with poor prognosis of smoking related lung adenocarcinoma using bioinformatics analysis JO - Int J Med Sci. VL - 15 UR - https://doi.org/10.7150/ijms.28728 DO - 10.7150/ijms.28728 ID - Zhang2018 ER - TY - JOUR AU - Tian, S. S. AU - Meng, G. AU - Zhang, W. PY - 2019 DA - 2019// TI - A six-mRNA prognostic model to predict survival in head and neck squamous cell carcinoma JO - Cancer Manag Res. VL - 11 UR - https://doi.org/10.2147/CMAR.S185875 DO - 10.2147/CMAR.S185875 ID - Tian2019 ER - TY - JOUR AU - Zhang, X. AU - Gao, P. AU - Yang, X. AU - Cai, J. AU - Ding, G. AU - Zhu, X. PY - 2018 DA - 2018// TI - Reduced selenium-binding protein 1 correlates with a poor prognosis in intrahepatic cholangiocarcinoma and promotes the cell epithelial–mesenchymal transition JO - Am J Transl Res. VL - 10 ID - Zhang2018 ER - TY - JOUR AU - Li, P. AU - Fan, H. AU - He, Q. PY - 2018 DA - 2018// TI - Investigation of the clinical significance and prognostic value of microRNA-145 in human hepatocellular carcinoma JO - Med (Baltimore). VL - 97 UR - https://doi.org/10.1097/MD.0000000000013715 DO - 10.1097/MD.0000000000013715 ID - Li2018 ER - TY - JOUR AU - Niyazi, M. AU - Pitea, A. AU - Mittelbronn, M. AU - Steinbach, J. AU - Sticht, C. AU - Zehentmayr, F. PY - 2016 DA - 2016// TI - A 4-miRNA signature predicts the therapeutic outcome of glioblastoma JO - Oncotarget. VL - 7 ID - Niyazi2016 ER - TY - JOUR AU - Wang, S. AU - Wang, Q. AU - Zhang, X. AU - Liao, X. AU - Wang, G. AU - Yu, L. PY - 2018 DA - 2018// TI - Distinct prognostic value of dynactin subunit 4 (DCTn4) and diagnostic value of DCTn1, DCTn2, and DCTn4 in colon adenocarcinoma JO - Cancer Manag Res. VL - 10 UR - https://doi.org/10.2147/CMAR.S183062 DO - 10.2147/CMAR.S183062 ID - Wang2018 ER - TY - JOUR AU - Guo, W. N. AU - Zhu, L. AU - Yu, M. AU - Zhu, R. AU - Chen, Q. AU - Wang, Q. PY - 2018 DA - 2018// TI - A five-DNA methylation signature act as a novel prognostic biomarker in patients with ovarian serous cystadenocarcinoma JO - Clin Epigenetics. VL - 10 UR - https://doi.org/10.1186/s13148-018-0574-0 DO - 10.1186/s13148-018-0574-0 ID - Guo2018 ER - TY - JOUR AU - Zhang, H. Z. AU - Ren, L. AU - Ding, Y. AU - Li, F. AU - Chen, X. AU - Ouyang, Y. PY - 2019 DA - 2019// TI - Hyaluronan-mediated motility receptor confers resistance to chemotherapy via TGFβ/Smad2-induced epithelial–mesenchymal transition in gastric cancer JO - FASEB J. VL - 33 UR - https://doi.org/10.1096/fj.201802186R DO - 10.1096/fj.201802186R ID - Zhang2019 ER - TY - JOUR AU - Poeta, M. L. AU - Massi, E. AU - Parrella, P. AU - Pellegrini, P. AU - Robertis, M. AU - Copetti, M. PY - 2012 DA - 2012// TI - Aberrant promoter methylation of beta-1,4 galactosyltransferase 1 as potential cancer-specific biomarker of colorectal tumors JO - Genes Chromosomes Cancer VL - 51 UR - https://doi.org/10.1002/gcc.21998 DO - 10.1002/gcc.21998 ID - Poeta2012 ER - TY - JOUR AU - Chen, J. AU - Luo, Y. AU - Yang, Z. AU - Wen, L. AU - Huang, L. PY - 2018 DA - 2018// TI - Knockdown of angiopoietin-like 4 inhibits the development of human gastric cancer JO - Oncol Rep VL - 39 ID - Chen2018 ER - TY - JOUR AU - Manandhar, S. AU - Kim, C. G. AU - Lee, S. H. AU - Kang, S. H. AU - Basnet, N. AU - Lee, Y. M. PY - 2017 DA - 2017// TI - Exostosin 1 regulates cancer cell stemness in doxorubicin-resistant breast cancer cells JO - Oncotarget. VL - 8 UR - https://doi.org/10.18632/oncotarget.19737 DO - 10.18632/oncotarget.19737 ID - Manandhar2017 ER - TY - JOUR AU - Whipple, C. A. AU - Lander, A. D. AU - Korc, M. PY - 2008 DA - 2008// TI - Discovery of a novel molecule that regulates tumor growth and metastasis JO - Sci World J VL - 8 UR - https://doi.org/10.1100/tsw.2008.152 DO - 10.1100/tsw.2008.152 ID - Whipple2008 ER - TY - JOUR AU - Das, T. P. AU - Suman, S. AU - Damodaran, C. PY - 2014 DA - 2014// TI - Induction of reactive oxygen species generation inhibits epithelial–mesenchymal transition and promotes growth arrest in prostate cancer cells JO - Mol Carcinog. VL - 53 UR - https://doi.org/10.1002/mc.22014 DO - 10.1002/mc.22014 ID - Das2014 ER - TY - JOUR AU - Wu, C. AU - Lin, J. AU - Chen, J. AU - Chang, C. AU - Weng, H. AU - Hsueh, C. PY - 2018 DA - 2018// TI - Integrated analysis of fine-needle-aspiration cystic fluid proteome, cancer cell secretome, and public transcriptome datasets for papillary thyroid cancerbiomarker discovery JO - Oncotarget. VL - 9 UR - https://doi.org/10.18632/oncotarget.23951 DO - 10.18632/oncotarget.23951 ID - Wu2018 ER - TY - JOUR AU - Warburg, O. PY - 1956 DA - 1956// TI - On the origin of cancer cells JO - Science VL - 123 UR - https://doi.org/10.1126/science.123.3191.309 DO - 10.1126/science.123.3191.309 ID - Warburg1956 ER - TY - JOUR AU - Ye, G. X. AU - Qin, Y. AU - Wang, S. AU - Pan, D. AU - Xu, S. AU - Wu, C. PY - 2019 DA - 2019// TI - Lamc1 promotes the Warburg effect in hepatocellular carcinoma cells by regulating PKM2 expression through AKT pathway JO - Cancer Biol Ther VL - 20 UR - https://doi.org/10.1080/15384047.2018.1564558 DO - 10.1080/15384047.2018.1564558 ID - Ye2019 ER - TY - JOUR AU - Lu, J. R. PY - 2019 DA - 2019// TI - The Warburg metabolism fuels tumor metastasis JO - Cancer Metastasis Rev. VL - 38 UR - https://doi.org/10.1007/s10555-019-09794-5 DO - 10.1007/s10555-019-09794-5 ID - Lu2019 ER - TY - JOUR AU - Fang, R. AU - Xiao, T. AU - Fang, Z. AU - Sun, Y. AU - Li, F. AU - Gao, Y. PY - 2012 DA - 2012// TI - MicroRNA-143 (miR-143) regulates cancer glycolysis via targeting hexokinase 2 gene JO - J Biol Chem VL - 287 UR - https://doi.org/10.1074/jbc.M112.373084 DO - 10.1074/jbc.M112.373084 ID - Fang2012 ER - TY - JOUR AU - Sinthupibulyakit, C. AU - Ittarat, W. AU - StClair, W. H. AU - StClair, D. K. PY - 2010 DA - 2010// TI - p53 protects lung cancer cells against metabolic stress JO - Int J Oncol. VL - 37 ID - Sinthupibulyakit2010 ER - TY - JOUR AU - FarahI, O. AU - Lewis, V. L. AU - Ayensu, W. K. AU - Cameron, J. A. PY - 2012 DA - 2012// TI - Therapeutic implications of the Warburg effect: role of oxalates and acetates on the differential survival of mrc-5 and a549 cell lines JO - Biomed Sci Instrum. VL - 48 ID - FarahI2012 ER - TY - JOUR AU - Kayser, G. AU - Sienel, W. AU - Kubitz, B. AU - Mattern, D. AU - Stickeler, E. AU - Passlick, B. PY - 2011 DA - 2011// TI - Poor outcome in primary non-small cell lung cancers is predicted by transketolase TKTL1 expression JO - Pathology. VL - 43 UR - https://doi.org/10.1097/PAT.0b013e32834c352b DO - 10.1097/PAT.0b013e32834c352b ID - Kayser2011 ER - TY - JOUR AU - Altenberg, B. AU - Greulich, K. O. PY - 2004 DA - 2004// TI - Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes JO - Genomics VL - 84 UR - https://doi.org/10.1016/j.ygeno.2004.08.010 DO - 10.1016/j.ygeno.2004.08.010 ID - Altenberg2004 ER - TY - JOUR AU - Li, X. AU - Gu, J. AU - Zhou, Q. PY - 2015 DA - 2015// TI - Review of aerobic glycolysis and its key enzymes—new targets for lung cancer therapy JO - Thorac Cancer. VL - 6 UR - https://doi.org/10.1111/1759-7714.12148 DO - 10.1111/1759-7714.12148 ID - Li2015 ER - TY - JOUR AU - Luo, F. AU - Liu, X. AU - Yan, N. AU - Li, S. AU - Cao, G. AU - Cheng, Q. PY - 2006 DA - 2006// TI - Hypoxia-inducible transcription factor-1 alpha promotes hypoxia induced A549 apoptosis via mechanism that involves the glycolysis pathway JO - BMC Cancer. VL - 6 UR - https://doi.org/10.1186/1471-2407-6-26 DO - 10.1186/1471-2407-6-26 ID - Luo2006 ER - TY - BOOK AU - Nelson, D. L. AU - Cox, M. M. PY - 2004 DA - 2004// TI - Lehninger principles of biochemistry PB - New York CY - WH Freeman ID - Nelson2004 ER - TY - JOUR AU - Minchenko, O. H. AU - Ogura, T. AU - OpentanovaI, L. AU - Minchenko, D. O. AU - Ochiai, A. AU - Caro, J. PY - 2005 DA - 2005// TI - 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphat gene family overexpression in human lung tumor JO - Ukr Biokhim Zh. VL - 77 ID - Minchenko2005 ER - TY - JOUR AU - Parnell, K. M. AU - Foulks, J. M. AU - Nix, R. N. AU - Clifford, A. AU - Bullough, J. AU - Luo, B. PY - 2013 DA - 2013// TI - Pharmacologic activation of PKM2 slows lung tumor xenograft growth JO - Mol Cancer Ther VL - 12 UR - https://doi.org/10.1158/1535-7163.MCT-13-0026 DO - 10.1158/1535-7163.MCT-13-0026 ID - Parnell2013 ER -