Elevated MR-proANP plasma concentrations are associated with sepsis and predict mortality in critically ill patients

Table 3 Correlations with MR-proANP plasma concentrations at ICU admission

Parameters	ICU patients
Parameters	R	p
Disease severity/clinical scoring/therapy
APACHE II	0.260	< 0.001
SOFA	0.223	0.011
SAPS	0.341	0.006
Fluid substitution	− 0.233	0.001
Markers of inflammation
White blood cell count	− 0.148	0.029
C-reactive protein	0.286	< 0.001
Procalcitonin	0.378	< 0.001
suPAR	0.493	< 0.001
NT-proCNP	0.683	< 0.001
Markers of organ function
NT-proBNP	0.740	< 0.001
Urea	0.623	< 0.001
Creatinine	0.629	< 0.001
GFR-cystatin C	− 0.675	< 0.001
Cystatin C	0.675	< 0.001
Lipase	− 0.191	0.012
Pancreatic amylase	− 0.317	0.006
Alanine aminotransferase	− 0.172	0.012
Glutamate dehydrogenase	− 0.151	0.037
Pseudocholinesterase activity	− 0.339	< 0.001
Albumin	−0.190	0.045
Total protein	− 0.263	< 0.001
INR	0.207	0.003
aPTT	0.324	< 0.001
Antithrombin III	− 0.216	0.015
Adipocytokines/metabolic markers
Adiponectin	0.434	0.001
Resistin	0.349	0.008
RBP4	0.306	0.012
HOMA-β	0.332	0.007
Parathyroid hormone	0.299	0.014
Calcium	− 0.288	< 0.001
Phosphorus	0.241	0.001

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