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Table 1 Participants’ demographic and serology results

From: Transient receptor potential melastatin 2 channels are overexpressed in myalgic encephalomyelitis/chronic fatigue syndrome patients

Category

Item

HC

ME/CFS

p value

General demographics

Age (years)

43.10 ± 4.089

43.50 ± 4.126

0.989

Gender

> 0.999

 Male (%, n)

(40%, 4)

(40%, 4)

 Female (%, n)

(60%, 6)

(60%, 6)

BMI (kg/m2)

23.41 ± 0.881

25.21 ± 0.937

0.120

WHODAS

1.382 ± 0.518

38.73 ± 5.504

< 0.0001

 Illness demographics (SF-36)

Pain (%)

85.91 ± 5.026

28.18 ± 7.971

< 0.0001

Physical Functioning (%)

98.64 ± 0.975

35.45 ± 6.085

< 0.0001

Role physical (%)

97.15 ± 1.547

13.08 ± 5.686

< 0.0001

General Health (%)

74.99 ± 4.171

30.67 ± 3.988

< 0.0001

Social functioning (%)

95.45 ± 3.049

28.41 ± 7.922

< 0.0001

Emotional wellbeing (%)

94.45 ± 3.049

74.02 ± 9.277

0.069

 Serology report

WBC

5.945 ± 0.371

6.909 ± 0.539

0.223

Lymphocytes

1.705 ± 0.127

1.947 ± 0.106

0.223

Neutrophils

3.575 ± 0.288

4.241 ± 0.501

0.519

Monocytes

0.466 ± 0.051

0.502 ± 0.051

0.467

Eosinophils

0.150 ± 0.031

0.518 ± 0.051

0.935

Basophils

0.046 ± 0.005

0.048 ± 0.006

0.955

Platelets

252.8 ± 24.12

246.8 ± 9.213

0.797

RBC

4.665 ± 0.102

4.808 ± 0.165

0.835

Haematocrit

0.416 ± 0.009

0.428 ± 0.013

0.618

Haemoglobin

136.2 ± 3.261

142.9 ± 4.089

0.339

  1. Data are represented as mean ± SEM using Mann Whitney U tests
  2. HC healthy controls, ME/CFS myalgic encephalomyelitis/chronic fatigue syndrome, BMI body mass index, RBC red blood cell, SF-36 short-form health survey, WBC white blood cell, WHODAS world health organisation disability assessment schedule
  3. *** p < 0.0001