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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Transient receptor potential melastatin 2 channels are overexpressed in myalgic encephalomyelitis/chronic fatigue syndrome patients

Fig. 4

Pharmacological effect of 8-Br-ADPR and N6-Bnz-cAMP drug treatment on TRPM2 and CD38 surface expression on NK cell subsets. On CD56BrightCD15Dim/− NK cells (a), TRPM2 surface expression significantly decreased following treatment with 8-Br-ADPR within the ME/CFS group. No significant difference was observed on the CD56DimCD16+ NK cell subset for TRPM2 surface expression between and within groups (b). Moreover, no significant differences between or within groups were found on theCD56BrightCD15Dim/− (c) and CD56DimCD16+ (d) NK cell subsets for dual expression with TRPM2

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