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Table 1 Baseline clinical and demographic characteristics

From: BMI, irAE, and gene expression signatures associate with resistance to immune-checkpoint inhibition and outcomes in renal cell carcinoma

Characteristic

 

Median age (range)—year

66 (17–92)

Female gender—no. (%)

25 (27.8%)

Ethnicity—no. (%)

 Caucasian

59 (65%)

 African American

8 (9%)

 Hispanic

5 (6%)

 Asian/Pacific Islander

3 (3%)

 Other/unknown

15 (17%)

Smoking history—no. (%)

 No

46 (51%)

BMI status—no. (%)

 Underweight

2 (2%)

 Normal

29 (32%)

 Overweight

38 (42%)

 Obese

21 (23%)

IMDC risk scorea—no. (%)

 Favorable

18 (20%)

 Intermediate

59 (65%)

 Poor

6 (6%)

No. of organs with metastasis—no. (%)

 1

8 (9%)

 > 2

73 (81%)

Most common sites of metastasis—no. (%)

 Lung

66 (73%)

 Spine

31 (34%)

 Liver

23 (25%)

 Brain

7 (8%)

Nephrectomy—no. (%)

74 (82%)

Previous radiotherapy—no. (%)

52 (58%)

ICI line of treatment—no. (%)

 First line

8 (9%)

 Second line

43 (48%)

 Third line

28 (31%)

 Fourth or more

11 (12%)

  1. aFavorable risk responds to an International Renal Cell Carcinoma Database Consortium (IMDC) score of 0, intermediate risk to a score of 1 or 2, poor risk to a score of 3 to 6