Table 1 The relationship between clinicopathological characteristics and 1-year mortality in patients with AWS (n = 115)
|  | Alive (n = 102) | Dead (n = 13) | p-value1 |
|---|---|---|---|
Age (years) | 48 (39–54) | 48 (35–60) | 0.915 |
Male/female | 75/27 | 13/0 | 0.035 |
BMI (kg/m2) | 22.6 (20.9–26.2) | 21.9 (18.8–29.2) | 0.473 |
Clinical | |||
 Alcohol intake (U/week)a | 205 (134–280) | 280 (140–350) | 0.390 |
 GMAWS (at presentation) | 4 (3, 4) | 4 (4–5) | 0.077 |
 GMAWS max | 4 (3–5) | 5 (4–6) | 0.090 |
 GMAWS max (< 4/≥ 4) | 38/63 | 1/12 | 0.033 |
 BDZ total (mg) | 130 (50–240) | 230 (55–320) | 0.148 |
 Smoker (yes/no) | 75/24 | 9/4 | 0.611 |
 Recent weight loss (yes/no) | 65/28 | 11/1 | 0.114 |
 Gait disturbance (yes/no) | 83/18 | 12/1 | 0.358 |
Laboratory | |||
 Bilirubin (umol/L) | 16 (10–28) | 31 (13–75) | 0.019 |
 Alk phos (U/L) | 106 (92–137) | 130 (95–180) | 0.154 |
 Albumin (g/L) | 39 (36–42) | 37 (27.5–40) | 0.106 |
 CRP (mg/L) | 4 (2–11) | 17 (7–30) | 0.004 |
 AST | 58 (34–98) | 78 (29–131) | 0.634 |
 ALT | 38 (25–61) | 35 (18–53) | 0.185 |
 AST:ALT | 1.6 (1.0–2.2) | 1.9 (1.5–3.4) | 0.038 |
 Urea (mmol/L) | 3.4 (2.6–4.8) | 3.2 (2.5–5.4) | 0.569 |
 Sodium (mmol/L) | 137 (134–140) | 138 (136–141) | 0.280 |
 Potassium (mmol/L) | 4.0 (3.7–4.4) | 4.0 (3.5–4.5) | 0.555 |
 Serum magnesium (mmol/L) | 0.72 (0.62–0.80) | 0.53 (0.48–0.72) | 0.006 |
 Plasma H+ (nmol/L) | 37 (33–40) | 33 (27–40) | 0.175 |
 Plasma HCO3− (mmol/L) | 27 (25–32) | 28 (24–35) | 0.745 |
 MCV (fl) | 95.4 (90.6–99.7) | 100.4 (93.1–106.7) | 0.059 |
 Platelets (109/L) | 239 (143–295) | 175 (78–240) | 0.092 |
 Whole blood TDP (ng/gHb) | 595 (509–825) | 670 (391–791) | 0.720 |
 LDH (U/L) | 257 (208–325) | 272 (220–369) | 0.373 |
 Glucose (mmol/L) | 5.8 (5.3–7.5) | 6.9 (5.9–7.7) | 0.183 |
 Lactate (mmol/L) | 2.3 (1.5–4.2) | 3.8 (2.6–7.2) | 0.011 |
 Follow-up ‘next admission’ serum magnesium (mmol/L) | 0.68 (0.59–0.76) | 0.61 (0.49–0.67) | 0.020 |
Medications | |||
 Thiamine (yes/no) | 77/23 | 2/11 | 0.978 |
 Magnesium (yes/no) | 8/88 | 13/0 | 0.282 |
 PPi (yes/no) | 59/40 | 4/9 | 0.506 |
 Diuretic (yes/no) | 5/91 | 4/9 | 0.002 |
Admission profile | |||
 Admitted within previous month (yes/no) | 23/75 | 3/10 | 0.975 |
 ED presentations within 12 months | 2 (1–5) | 3 (2–7) | 0.315 |
 Total number of admissions | 14 (6–32) | 14 (4–57) | 0.466 |
 Length of stay (days) | 4 (3–7) | 8 (5–10) | 0.027 |