Table 3 Univariate and multivariate analysis of OS
Variable (comparator) | Overall survival | |||
|---|---|---|---|---|
Univariate analysis | Multivariate analysis | |||
HR (95% CI) | p-value | HR (95% CI) | p-value | |
Early ir-fatigue | ||||
Yes vs no | 2.63 (1.83–3.77) | < 0.0001 | 2.32 (1.59–3.38) | < 0.0001 |
Sex | ||||
Male vs female | 1.41 (0.97–2.05) | 0.0669 | – | – |
Age at diagnosis | ||||
Elderly vs non-elderly | 1.35 (0.96–1.89) | 0.0758 | – | – |
Primary tumor (melanoma) | ||||
NSCLC | 2.24 (1.52–3.28) | < 0.0001 | 1.72 (1.14–2.60) | 0.0095 |
Renal cell carcinoma | 1.62 (0.99–2.63) | 0.0518 | 1.40 (0.82–2.37) | 0.2101 |
Others | 0.74 (0.10–5.38) | 0.7679 | 0.58 (0.07–4.29) | 0.5992 |
Treatment line | ||||
Non-first vs first | 1.58 (1.08–2.31) | 0.0170 | 1.33 (0.88–2.01) | 0.1717 |