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Table 3 Patient characteristics

From: Hypercholesterolemia-induced increase in plasma oxidized LDL abrogated pro angiogenic response in kidney grafts

 

Normocholesterolemia

Hypercholesterolemia

Donors

Donors

Age (years)

43 ± 9

53 ± 11

Traumatic death (%, n)

29 (2)

33 (3)

Hemorrhagic and ischemic stroke (%, n)

71 (5)

67 (6)

Anastomosis time (min)

42 ± 12

43 ± 9

Cold ischemia time (min)

888 ± 87

870 ± 180

eGFRa

81 ± 8

81 ± 6

 

Recipients

Recipients

Number

7

9

Age (years)

45 ± 15

50 ± 14

Male gender (%, n)

86 (6)

56 (5)

Dialysis duration (months)

16 ± 9

6 ± 13*

Current smoker (%, n)

71 (5)

22 (2)*

Diabetes mellitus (%, n)

14 (1)

0 (0)

Hypertension (%, n)

86 (6)

78 (7)

Statin (%, n)

57 (4)

44 (4)

Cholesterolemia the day before surgery (mmol/L)

3.80 ± 0.54

6.04 ± 1.08*

Cholesterolemia at 3 months (mmol/L)

4.80 ± 0.47

5.78 ± 1.48

Cholesterolemia at 6 months (mmol/L)

4.32 ± 1.13

4.91 ± 1.19

Cholesterolemia at 12 months (mmol/L)

4.72 ± 1.09

5.10 ± 0.50

eGFRa at 1 month

48 ± 17

45 ± 25

eGFRa at 3 months

53 ± 23

50 ± 18

eGFRa at 12 months

64 ± 13

44 ± 13*

Urinary ratio protein/creatinine (mg/mmol) at 3 month

31.4 ± 21.2

73.9 ± 42.5

Urinary ratio protein/creatinine (mg/mmol) at 12 month

16.7 ± 5.2

78.6 ± 80.4*

  1. Values are mean ± SD
  2. * p < 0.05 vs. normocholesterolemia
  3. aeGFR: estimated glomerular filtration rate according to the MDRD formula (mL/min/1.73 m2)