Identification of a serum-based miRNA signature for response of esophageal squamous cell carcinoma to neoadjuvant chemotherapy

Table 3 Univariate binary logistic regression for preoperative chemotherapy response

Variables	OR	95% CI Low	95% CI High	P
Age (years)
≥ 65 vs < 65	0.55	0.17	1.8	0.31
Sex
Male vs female	0.73	0.15	3.7	0.70
cT
3, 4 vs 0, 1, 2	1.42	0.43	4.7	0.57
cN
Positive vs negative	1.17	0.22	6.2	0.85
Serum SCC antigen (ng/ml)
≥ 1.5 vs < 1.5	0.39	0.13	1.2	0.11
miR-23a-5p
High vs low	2.80	0.90	8.8	0.08
miR-193b-5p
High vs low	7.47	0.93	60.2	0.06
miR-873-3p
High vs low	3.11	0.96	10.1	0.06

OR odds ratio, CI confidence interval, cT clinical T, cN clinical N, SCC squamous cell carcinoma

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