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Table 2 Clinical features stratified by response to preoperative chemotherapy (n = 84)

From: Identification of a serum-based miRNA signature for response of esophageal squamous cell carcinoma to neoadjuvant chemotherapy

Variables Response P
Grade 0, 1 Grade 2, 3
Sex
 Female 12 2 1.00
 Male 57 13  
Age
 Years 65 (41–77) 66 (30–76) 0.56
cT
 1 8 3 0.78
 2 10 2  
 3 49 10  
 4 2 0  
cN
 0 8 2 0.80
 1 38 9  
 2 20 3  
 3 3 1  
cStage
 1 2 1 0.75
 2 18 4  
 3 45 9  
 4 4 1  
pT
 0 0 4 > 0.0001
 1 17 6  
 2 15 4  
 3 29 0  
 4 8 1  
pN
 0 24 5 0.90
 1 22 6  
 2 13 3  
 3 10 1  
pStage
 0 0 2 0.07
 1 14 3  
 2 21 6  
 3 29 4  
 4 5 0  
Differentiation
 Well or moderate 56 11 0.340
 Poor 10 0  
Lymphatic invasion
 < 2 23 8 0.250
 ≥ 2 46 7  
Venous invasion
 < 20 50 9 0.36
 ≥ 20 19 6  
Pretreatment CEA
 ng/ml 2.6 (1.0–6.0) 1.9 (0.4–4.3) 0.060
Pretreatment SCC
 ng/ml 1.1 (0.5–6.4) 1.4 (0.6–6.7) 0.350
  1. cT clinical T, cN clinical N, cStage clinical Stage, pT pathological T, pN pathological N, pStage pathological Stage, CEA carcinoembryonic antigen, SCC squamous cell carcinoma
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