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Table 2 Clinical features stratified by response to preoperative chemotherapy (n = 84)

From: Identification of a serum-based miRNA signature for response of esophageal squamous cell carcinoma to neoadjuvant chemotherapy

Variables

Response

P

Grade 0, 1

Grade 2, 3

Sex

 Female

12

2

1.00

 Male

57

13

 

Age

 Years

65 (41–77)

66 (30–76)

0.56

cT

 1

8

3

0.78

 2

10

2

 

 3

49

10

 

 4

2

0

 

cN

 0

8

2

0.80

 1

38

9

 

 2

20

3

 

 3

3

1

 

cStage

 1

2

1

0.75

 2

18

4

 

 3

45

9

 

 4

4

1

 

pT

 0

0

4

> 0.0001

 1

17

6

 

 2

15

4

 

 3

29

0

 

 4

8

1

 

pN

 0

24

5

0.90

 1

22

6

 

 2

13

3

 

 3

10

1

 

pStage

 0

0

2

0.07

 1

14

3

 

 2

21

6

 

 3

29

4

 

 4

5

0

 

Differentiation

 Well or moderate

56

11

0.340

 Poor

10

0

 

Lymphatic invasion

 < 2

23

8

0.250

 ≥ 2

46

7

 

Venous invasion

 < 20

50

9

0.36

 ≥ 20

19

6

 

Pretreatment CEA

 ng/ml

2.6 (1.0–6.0)

1.9 (0.4–4.3)

0.060

Pretreatment SCC

 ng/ml

1.1 (0.5–6.4)

1.4 (0.6–6.7)

0.350

  1. cT clinical T, cN clinical N, cStage clinical Stage, pT pathological T, pN pathological N, pStage pathological Stage, CEA carcinoembryonic antigen, SCC squamous cell carcinoma