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Table 3 Hub genes identified in the PPI networks

From: Identification of potential miRNA–mRNA regulatory network contributing to pathogenesis of HBV-related HCC

Upregulated DE-miRNAs Downregulated DE-miRNAs
Gene symbol Degree Gene symbol Degree
TP53 336 TP53 248
UBC 274 UBA52 193
RPS27A 255 MYC 177
GAPDH 249 AKT1 165
MYC 223 UBB 163
PHLPP2 215 EGFR 149
HSP90AA1 209 JUN 144
TOP2A 205 HSP90AA1 140
MAPK1 203 PIK3CA 134
JUN 193 ACLY 119