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Table 3 Hub genes identified in the PPI networks

From: Identification of potential miRNA–mRNA regulatory network contributing to pathogenesis of HBV-related HCC

Upregulated DE-miRNAs

Downregulated DE-miRNAs

Gene symbol

Degree

Gene symbol

Degree

TP53

336

TP53

248

UBC

274

UBA52

193

RPS27A

255

MYC

177

GAPDH

249

AKT1

165

MYC

223

UBB

163

PHLPP2

215

EGFR

149

HSP90AA1

209

JUN

144

TOP2A

205

HSP90AA1

140

MAPK1

203

PIK3CA

134

JUN

193

ACLY

119