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Table 1 Translational evidence for dairy milk exosome-mediated pathologies of western diseases

From: Exosomes of pasteurized milk: potential pathogens of Western diseases

Milk exosome component Potential pathogenic involvement
miR-148a Atherosclerosis, obesity, type 2 diabetes mellitus, hyperphagia, prostate cancer, breast cancer, hepatitis B-associated hepatocellular carcinoma, osteoporosis
miR-21 Adipogenesis, fetal macrosomia, prostate cancer, breast cancer, osteoporosis, hepatocellular carcinoma, diffuse large B-cell lymphoma
miR-29b Type 2 diabetes mellitus
miR-155 Breast cancer, hepatitis C-associated hepatocellular carcinoma, diffuse large B-cell lymphoma, Parkinson’s disease, prostate cancer
TGF-β Breast cancer, prostate cancer, osteoclastogenesis
Exosome lipids Parkinson’s disease