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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: PRAME promotes epithelial-to-mesenchymal transition in triple negative breast cancer

Fig. 5

PRAME induces an epithelial-to-mesenchymal transition towards a more mesenchymal phenotype. a Protein expression and densitometric quantification of epithelial (E-Cadherin) and mesenchymal (Vimentin, N-Cadherin) markers in PRAME TNBC cell line models. N-Cadherin expression could not be detected in the MDA-MB-468 cell line. *p ≤ 0.05; **p ≤ 0.01. b Representative immunofluorescence image of E-cadherin, demonstrating subcellular redistribution in PRAME overexpressing cells. Magnification ×40. DAPI, blue; E-Cadherin, green. Insert at 130% zoom

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